Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10565203 | 0.99 | S1PR1 (0.42) | S1PR1S1PR3ALDH1A1ABCB1HRH1 | |
| SCHEMBL9808381 | 0.88 | SCN1A (0.44) | ALDH1A1ABCB1KDM4EEGFRLTA4H | |
| Hydrochloric Acid SCHEMBL9808512 | 0.87 | SCN1A (0.43) | ALDH1A1ABCB1KDM4ELTA4HMEN1 | |
| SCHEMBL9808422 | 0.80 | ABCB1 (0.58) | ALDH1A1ABCB1KDM4ELTA4H | |
| SCHEMBL9808398 | 0.79 | ABCB1 (0.60) | ALDH1A1ABCB1KDM4ELTA4H | |
| Hydrochloric Acid SCHEMBL9808527 | 0.79 | ABCB1 (0.57) | ALDH1A1ABCB1LTA4H | |
| Hydrochloric Acid SCHEMBL9808486 | 0.78 | ABCB1 (0.59) | ALDH1A1ABCB1KDM4EEGFRLTA4H | |
| SCHEMBL9316458 | 0.78 | MGLL (0.42) | ALDH1A1ABCB1NPC1RAB9A | |
| SCHEMBL9808491 | 0.77 | MEN1 (0.56) | ALDH1A1ABCB1KDM4EEGFRLTA4H | |
| Hydrochloric Acid SCHEMBL9808395 | 0.76 | ALDH1A1 (0.57) | ALDH1A1ABCB1EGFRLTA4HMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266336-B1 | 1-[3-(2-Dialkylaminoethoxy)-2-thienyl]-3-phenyl-1-propanones and their acid addition salts, process for their preparation and pharmaceutical compositions containing them | Binder, Dieter, Prof. Dr. (AT) | 1991-05-15 | — | — | EP | claimed |
| EP-0266336-A1 | 1-[3-(2-Dialkylaminoethoxy)-2-thienyl]-3-phenyl-1-propanones and their acid addition salts, process for their preparation and pharmaceutical compositions containing them | Binder, Dieter, Prof. Dr. (AT) | 1988-05-04 | — | — | EP | claimed |
| EP-0266336-B1 | 1-[3-(2-Dialkylaminoethoxy)-2-thienyl]-3-phenyl-1-propanones and their acid addition salts, process for their preparation and pharmaceutical compositions containing them | Binder, Dieter, Prof. Dr. (AT) | 1991-05-15 | — | — | EP | disclosed |
| US-4814330-A | CARDIOVASCULAR DISORDERS | BINDER DIETER (AT) | 1989-03-21 | — | — | US | disclosed |