Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.42 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9200139 | 0.81 | CYP11B1 (0.64) | PPARGPRKAG1PRKAA1PRKAB1CYP11B1 | |
| SCHEMBL8874522 | 0.80 | MEN1 (0.53) | PPARGPRKAG1PRKAA1PRKAB1CYP11B1 | |
| SCHEMBL8700579 | 0.75 | PPARG (0.61) | PPARG | |
| SCHEMBL1844592 | 0.73 | LMNA (0.49) | PPARGPRKAG1PRKAA1PRKAB1ACHE | |
| SCHEMBL22533662 | 0.71 | CYP11B1 (0.38) | DPP4CYP11B1CYP11B2MAPK1HTT | |
| SCHEMBL27244064 | 0.71 | LMNA (0.46) | CYP11B1CYP11B2HTTSMN1; SMN2GSK3B | |
| SCHEMBL29424864 | 0.71 | CYP11B1 (0.38) | DPP4CYP11B1CYP11B2MAPK1HTT | |
| SCHEMBL7991782 | 0.70 | PRKAG1 (0.43) | PPARGPRKAG1PRKAA1PRKAB1ACHE | |
| SCHEMBL30084338 | 0.69 | PRKAG1 (0.43) | PPARGPRKAG1PRKAA1PRKAB1ACHE | |
| SCHEMBL29258938 | 0.69 | PRKAG1 (0.43) | PPARGPRKAG1PRKAA1PRKAB1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5321137-A | Process for the preparation of imidazopyridines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-06-14 | — | — | US | claimed |
| JP-6157526-A | — | — | None | — | — | JP | disclosed |
| JP-H06157526-A | PREPARATION OF IMIDAZOPYRIDINE | MERCK PATENT GMBH | 1994-06-03 | — | — | JP | disclosed |