Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 6/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30716899 | 0.85 | LMNA (0.38) | ALDH1A1KMT2ALMNAMAPTTSHR | |
| SCHEMBL5189158 | 0.80 | ATM (0.42) | ALDH1A1KMT2ALMNAMAPTGAA | |
| SCHEMBL5310249 | 0.76 | LMNA (0.34) | CA1CA2ALDH1A1KMT2ALMNA | |
| SCHEMBL10608062 | 0.76 | MEN1 (0.39) | ALDH1A1KMT2ALMNA | |
| SCHEMBL9756282 | 0.75 | TSHR (0.42) | LPAR1ALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL9101570 | 0.75 | LMNA (0.38) | ALDH1A1KMT2ALMNAMAPTTSHR | |
| SCHEMBL6367227 | 0.75 | MCOLN3 (0.55) | ACHEALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL30667146 | 0.75 | LMNA (0.38) | ALDH1A1KMT2ALMNAMAPTTSHR | |
| SCHEMBL531432 | 0.75 | LMNA (0.47) | ACHEALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL30666645 | 0.75 | LMNA (0.38) | ALDH1A1KMT2ALMNAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603314-A4 | CHEMICAL COMPOUNDS. | SMITHKLINE BEECHAM CORP (US) | 1994-08-24 | — | — | EP | disclosed |
| EP-0603314-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-06-29 | — | — | EP | disclosed |