Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 4/20 | 0.38 |
| ▸ | HTR7 | P34969 | 4/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL531432 | 0.77 | LMNA (0.47) | MEN1KMT2ALMNAL3MBTL1ALDH1A1 | |
| SCHEMBL29231947 | 0.77 | TACR1 (0.39) | KMT2ALMNAL3MBTL1ALDH1A1 | |
| SCHEMBL17666797 | 0.76 | KAT6A (0.37) | MEN1KMT2ALMNAADRB2ADRB1 | |
| SCHEMBL20583465 | 0.76 | ATM (0.36) | MEN1KMT2ALMNAL3MBTL1NR3C1 | |
| SCHEMBL9316798 | 0.76 | LPAR1 (0.42) | KMT2ALMNAALDH1A1 | |
| SCHEMBL15988245 | 0.75 | ALDH1A1 (0.40) | MEN1KMT2ALMNAL3MBTL1ALDH1A1 | |
| SCHEMBL9615904 | 0.74 | RORC (0.39) | MEN1KMT2ALMNAL3MBTL1NR3C1 | |
| SCHEMBL9724989 | 0.74 | RORC (0.39) | MEN1KMT2ALMNAL3MBTL1NR3C1 | |
| SCHEMBL20583291 | 0.73 | POLB (0.32) | MEN1KMT2AL3MBTL1NR3C1ALDH1A1 | |
| SCHEMBL10608140 | 0.73 | KMT2A (0.47) | KMT2ALMNAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0113910-B1 | ISOCARBOSTYRIL DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1989-10-11 | — | — | EP | disclosed |
| US-4526893-A | Pharmaceuticals | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1985-07-02 | — | — | US | disclosed |
| EP-0113910-A1 | Isocarbostyril derivatives, processes for their preparation and pharmaceutical compositions containing them | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1984-07-25 | — | — | EP | disclosed |