Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 5/20 | 0.75 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.75 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.75 |
| ▸ | DRD2 | P14416 | 7/20 | 0.53 |
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9274801 | 0.91 | ADRA1A (0.79) | ADRA1DADRA1AADRA1BDRD2HTR1A | |
| SCHEMBL9194060 | 0.90 | ADRA1A (0.89) | ADRA1DADRA1AADRA1BDRD2HTR1A | |
| Hydrochloric Acid SCHEMBL9316958 | 0.89 | ADRA1A (0.88) | ADRA1DADRA1AADRA1BDRD2HTR1A | |
| SCHEMBL9201007 | 0.89 | ADRA1A (0.82) | ADRA1DADRA1AADRA1BDRD2HTR1A | |
| SCHEMBL9195487 | 0.87 | ADRA1A (0.80) | ADRA1DADRA1AADRA1BDRD2HTR1A | |
| SCHEMBL5597266 | 0.86 | ADRA1D (1.00) | ADRA1DADRA1AADRA1BDRD2HTR1A | |
| SCHEMBL9317007 | 0.86 | ADRA1D (0.87) | ADRA1DADRA1AADRA1BDRD2HTR1A | |
| SCHEMBL9193925 | 0.86 | ADRA1D (0.87) | ADRA1DADRA1AADRA1BDRD2HTR1A | |
| SCHEMBL9132478 | 0.86 | ADRA1D (0.56) | ADRA1DADRA1AADRA1BDRD2HTR1A | |
| SCHEMBL9468889 | 0.85 | ADRA1A (0.75) | ADRA1DADRA1AADRA1BDRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5330985-A | Adrenergic blocking agents; urogenital disorders | SYNTHELABO (FR) | 1994-07-19 | — | — | US | disclosed |