Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 3/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.41 |
| ▸ | BPTF | Q12830 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GLP1R | P43220 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2614925 | 0.82 | BPTF (0.55) | SMN1; SMN2LMNAAURKAAURKBBPTF | |
| SCHEMBL11034032 | 0.79 | MAPT (0.63) | SMN1; SMN2LMNAMAPTPOLBGAA | |
| SCHEMBL63292 | 0.79 | LMNA (0.50) | SMN1; SMN2LMNAAURKAAURKBBPTF | |
| SCHEMBL10464337 | 0.78 | GLP1R (0.44) | SMN1; SMN2LMNAAURKAAURKBBPTF | |
| SCHEMBL11033911 | 0.78 | PPARA (0.49) | SMN1; SMN2AURKAAURKBBPTFMAPT | |
| SCHEMBL8666206 | 0.77 | SMN1; SMN2 (0.78) | SMN1; SMN2LMNAMAPTKMT2AKDM4E | |
| SCHEMBL25388143 | 0.75 | KCNH2 (0.45) | SMN1; SMN2LMNAAURKAAURKBBPTF | |
| SCHEMBL30514119 | 0.75 | KCNH2 (0.45) | SMN1; SMN2LMNAAURKAAURKBBPTF | |
| SCHEMBL29887304 | 0.74 | MAPT (0.49) | SMN1; SMN2LMNAAURKAAURKBMAPT | |
| SCHEMBL23413256 | 0.74 | MAPT (0.49) | SMN1; SMN2LMNAAURKAAURKBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5280009-A | Herbicide | BASF AKTIENGESELLSCHAFT (DE) | 1994-01-18 | — | — | US | disclosed |
| EP-0523533-A1 | Substituted pyrimidin derivatives and their use for combatting the growth of undesirable plants | BASF Aktiengesellschaft (DE) | 1993-01-20 | — | — | EP | disclosed |