SCHEMBL63292

SCHEMBL63292

CS(=O)(=O)c1nc(Cl)cc(Cl)n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
GLP1R P43220 10/20 0.38
BPTF Q12830 1/20 0.37
NPSR1 Q6W5P4 3/20 0.36
TLR9 Q9NR96 3/20 0.36
SDHB P21912 3/20 0.36
STAT3 P40763 2/20 0.36
STAT1 P42224 2/20 0.36
RAB9A P51151 2/20 0.36
KMT2A Q03164 2/20 0.36
TP53 P04637 2/20 0.36
MAPK1 P28482 2/20 0.36
HTT P42858 2/20 0.36
HSD17B10 Q99714 2/20 0.36
MEN1 O00255 1/20 0.36
S1PR4 O95977 1/20 0.36
POLB P06746 1/20 0.36
HPGD P15428 1/20 0.36
S1PR1 P21453 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11585339 0.87 LMNA (0.44) LMNASMN1; SMN2GLP1RBPTFNPSR1
SCHEMBL6296316 0.87 LMNA (0.44) LMNASMN1; SMN2GLP1RSDHBKMT2A
SCHEMBL29010137 0.86 POLB (0.41) LMNASMN1; SMN2GLP1RKMT2AHTT
SCHEMBL8597269 0.85 LMNA (0.42) LMNASMN1; SMN2GLP1RBPTFNPSR1
SCHEMBL11107779 0.85 LMNA (0.47) LMNASMN1; SMN2GLP1RBPTFNPSR1
SCHEMBL13703901 0.85 LMNA (0.42) LMNASMN1; SMN2GLP1RBPTFNPSR1
SCHEMBL8666206 0.83 SMN1; SMN2 (0.78) LMNASMN1; SMN2GLP1RNPSR1TLR9
SCHEMBL2614925 0.82 BPTF (0.55) LMNASMN1; SMN2BPTFRAB9AAURKA
SCHEMBL20578730 0.82 SDHB (0.42) LMNASMN1; SMN2GLP1RNPSR1TLR9
SCHEMBL9636006 0.82 LMNA (0.40) LMNASMN1; SMN2GLP1RBPTFNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 504 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106866547-B Synthesis method of 2-ethoxy-4, 6-dichloropyrimidine 江苏省农用激素工程技术研究中心有限公司 2020-11-10 CN claimed
CN-106866547-A The synthetic method of the dichloro pyrimidine of 2 ethyoxyl 4,6 江苏省农用激素工程技术研究中心有限公司 2017-06-20 CN claimed
JP-5202000-A None JP disclosed
US-20260146124-A1 RESIN COMPOSITION AND USES OF THE SAME TAIWAN UNION TECHNOLOGY CORPORATION (TW) 2026-05-28 US disclosed
CN-122071610-A Resin composition and use thereof 台燿科技股份有限公司 2026-05-22 CN disclosed
CN-122055400-A Composition, prepreg and metal-clad laminate AGC株式会社 2026-05-15 CN disclosed
CN-122039076-A Preparation method of 2-methyl sulfoxide pyrimidine derivative 石河子大学 2026-05-15 CN disclosed
US-20260130921-A1 TREATMENT OF VIRAL INFECTIONS WITH COMBINATION OF PIKFYVE KINASE INHIBITORS AND TMPRSS-2 INHIBITORS AcuraStem Incorporated (US) 2026-05-14 US disclosed
CN-122029231-A Resin composition, prepreg, metal-clad laminate, and method for producing same AGC株式会社 2026-05-12 CN disclosed
US-20260085154-A1 POLYMER, COMPOSITION, CURED PRODUCT, LAMINATED BODY, AND ELECTRONIC COMPONENT JSR CORPORATION (JP) 2026-03-26 US disclosed
EP-4710923-A2 INDOLE AHR INHIBITORS AND USES THEREOF Ikena Oncology, Inc. (US) 2026-03-18 EP disclosed
US-4126609-A AZO DYESTUFF WITH A FIBER-REACTIVE GROUP ATTACHED TO A NAPHTHALENE SULPHONIC ACID COMPONENT BAYER AKTIENGESELLSCHAFT (DE) 1978-11-21 US disclosed
US-4122079-A Reactive azo dyestuffs from diazotized sulfo-amino naphthalenes and diaminosulfobenzenes BAYER AKTIENGESELLSCHAFT (DE) 1978-10-24 US disclosed
US-4118382-A DYES FOR CELLULOSE, WOOL, SILK, POLYAMIDE, AND POLYURETHANE FIBERS BAYER AKTIENGESELLSCHAFT (DE) 1978-10-03 US disclosed
US-4089895-A COUPLER FOR AZO DYES BAYER AKTIENGESELLSCHAFT (DT) 1978-05-16 US disclosed
US-4065446-A Reactive dyestuffs containing urea alkylene linkage between chromophore and reactive radical BAYER AKTIENGESELLSCHAFT (DT) 1977-12-27 US disclosed
US-4049704-A AZO REACTIVE DYES BAYER AKTIENGESELLSCHAFT (DT) 1977-09-20 US disclosed
US-3989692-A PHTHALOCYANINE DYES, WOOL, SILK, POLYAMIDES, CELLULOSE BAYER AKTIENGESELLSCHAFT (DT) 1976-11-02 US disclosed
US-3988310-A FIBER-REACTIVE DYES; CELLULOSE BAYER AKTIENGESELLSCHAFT (DT) 1976-10-26 US disclosed
US-3957751-A WATER-SOLUBLE REACTIVE DYESTUFFS OF THE MONOAZO SERIES CONTAINING AN ACTIVE METHYLENE COUPLING COMPONENT HOECHST AKTIENGESELLSCHAFT (DT) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260130921-A1 TREATMENT OF VIRAL INFECTIONS WITH COMBINATION OF PIKFYVE KINASE INHIBITORS AND TMPRSS-2 INHIBITORS TMPRSS2, TMPRSS11D, TMPRSS6 LMNA 4375/4885SMN1; SMN2 2706/4885GLP1R 2028/4885
US-20260146124-A1 RESIN COMPOSITION AND USES OF THE SAME ARCN1, ASH2L, ITGA1 LMNA 1292/4885SMN1; SMN2 894/4885GLP1R 3694/4885
US-20260085154-A1 POLYMER, COMPOSITION, CURED PRODUCT, LAMINATED BODY, AND ELECTRONIC COMPONENT RER1, COL1A1, SMC1A LMNA 147/4885SMN1; SMN2 457/4885GLP1R 1879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.