Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 5/20 | 0.44 |
| ▸ | AURKA | O14965 | 2/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.38 |
| ▸ | BPTF | Q12830 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10463557 | 0.81 | PTGS2 (0.50) | BPTFPTGS2 | |
| SCHEMBL10463555 | 0.81 | PTGS2 (0.50) | BPTFPTGS2 | |
| SCHEMBL2614925 | 0.81 | BPTF (0.55) | AURKAAURKBBPTFPTGS2LMNA | |
| SCHEMBL9317008 | 0.78 | SMN1; SMN2 (0.46) | GLP1RAURKAAURKBBPTFPTGS2 | |
| SCHEMBL63292 | 0.78 | LMNA (0.50) | GLP1RAURKAAURKBBPTFLMNA | |
| SCHEMBL1748325 | 0.74 | GAA (0.48) | GLP1RTRPM8GAATDP1 | |
| SCHEMBL11033911 | 0.73 | PPARA (0.49) | AURKAAURKBBPTFPTGS2SMN1; SMN2 | |
| SCHEMBL9493382 | 0.73 | GAA (0.52) | LMNATRPM8GAATDP1 | |
| SCHEMBL12411085 | 0.73 | MEN1 (0.44) | AURKAAURKBTRPM8GAATDP1 | |
| SCHEMBL12102888 | 0.72 | GSK3B (0.50) | AURKAAURKBLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4941910-A | 4-halo-2-oxy or sulfonyl-4-amino substituted pyrimidines as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-07-17 | — | — | US | disclosed |
| EP-0332963-A1 | Pyrimidine derivatives | BAYER AG (DE) | 1989-09-20 | — | — | EP | disclosed |