1-Hydroxyanthraquinone

1-Hydroxyanthraquinone

SCHEMBL9317010

O=C1c2cccc(O)c2C(=O)c2c(O)ccc(O)c21.O=C1c2ccccc2C(=O)c2c(O)cccc21

nearest known ligand 0.80

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.80
MAOA P21397 6/20 0.80
ALDH1A1 P00352 6/20 0.80
TDP1 Q9NUW8 6/20 0.80
MAPK1 P28482 5/20 0.80
HPGD P15428 5/20 0.80
SMN1; SMN2 Q16637 4/20 0.80
ALOX15 P16050 4/20 0.80
HSD17B10 Q99714 4/20 0.80
LMNA P02545 3/20 0.80
TSHR P16473 3/20 0.80
MAOB P27338 2/20 0.80
HTT P42858 1/20 0.80
MEN1 O00255 8/20 0.76
KMT2A Q03164 8/20 0.76
MCL1 Q07820 4/20 0.63
KDM4E B2RXH2 4/20 0.63
CYP3A4 P08684 4/20 0.63
RECQL P46063 4/20 0.63
APEX1 P27695 3/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Danthron SCHEMBL9317014 1.00 MAPT (0.80) MAPTMAOAALDH1A1TDP1MAPK1
Anthrarufin SCHEMBL11422341 0.96 MAPT (0.83) MAPTMAOAALDH1A1TDP1MAPK1
SCHEMBL3198327 0.94 MAOA (0.86) MAPTMAOAALDH1A1TDP1MAPK1
SCHEMBL30695844 0.94 MAOA (0.86) MAPTMAOAALDH1A1TDP1MAPK1
1-Hydroxyanthraquinone SCHEMBL145303 0.94 MAOA (0.86) MAPTMAOAALDH1A1TDP1MAPK1
Anthrarufin SCHEMBL25355428 0.94 MAOA (0.86) MAPTMAOAALDH1A1TDP1MAPK1
1-Hydroxyanthraquinone SCHEMBL30912125 0.94 MAOA (0.86) MAPTMAOAALDH1A1TDP1MAPK1
1-Hydroxyanthraquinone SCHEMBL1893347 0.92 MAOA (0.83) MAPTMAOAALDH1A1TDP1MAPK1
Quinalizarin SCHEMBL9308575 0.91 MAOA (0.80) MAPTMAOAALDH1A1TDP1MAPK1
Danthron SCHEMBL29356886 0.89 MAPT (1.00) MAPTMAOAALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5322634-A Electrorheological fluids comprising phenoxy organometallic salt particulate FORD MOTOR COMPANY (US) 1994-06-21 US claimed