Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | KLK1 | P06870 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26903783 | 0.84 | CES2 (0.68) | NPC1RAB9ACES2CES1LCK | |
| SCHEMBL29462782 | 0.84 | CES2 (0.68) | NPC1RAB9ACES2CES1LCK | |
| SCHEMBL546633 | 0.84 | CES2 (0.68) | NPC1RAB9ACES2CES1LCK | |
| Hydrochloric Acid SCHEMBL8358165 | 0.82 | CES2 (0.65) | NPC1RAB9ACES2CES1LCK | |
| Hydrochloric Acid SCHEMBL30932950 | 0.82 | CES2 (0.65) | NPC1RAB9ACES2CES1LCK | |
| Hydrochloric Acid SCHEMBL22558829 | 0.82 | CES2 (0.65) | NPC1RAB9ACES2CES1LCK | |
| Hydrochloric Acid SCHEMBL8169297 | 0.82 | CES2 (0.65) | NPC1RAB9ACES2CES1LCK | |
| SCHEMBL9317358 | 0.80 | ALDH1A1 (0.53) | NPC1RAB9ACES2CES1LCK | |
| SCHEMBL9317045 | 0.80 | CES2 (0.57) | CES2CES1LCKPLAUF2 | |
| Benzamide SCHEMBL28130612 | 0.79 | MAPT (0.64) | NPC1RAB9ACES2CES1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524941-A4 | — | — | 1994-08-31 | — | — | EP | disclosed |
| EP-0524941-A1 | MONOAZO PIGMENT COMPOSITIONS. | SUN CHEMICAL CORP (US) | 1993-02-03 | — | — | EP | disclosed |
| WO-1991014744-A1 | MONOAZO PIGMENT COMPOSITIONS | SUN CHEMICAL CORPORATION (US) | 1991-10-03 | — | — | WO | disclosed |
| US-5024698-A | Axomethine containing printing ink | SUN CHEMICAL CORPORATION (US) | 1991-06-18 | — | — | US | disclosed |