Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9317414 | 1.00 | TSHR (0.42) | TSHRALDH1A1CYP3A4PTGS1HSD17B3 | |
| SCHEMBL9318859 | 0.88 | NPC1 (0.43) | TSHRALDH1A1CYP3A4PTGS1HPGD | |
| SCHEMBL9318866 | 0.88 | NPC1 (0.43) | TSHRALDH1A1CYP3A4PTGS1HPGD | |
| SCHEMBL9317154 | 0.86 | POLB (0.40) | TSHRALDH1A1PTGS1HSD17B3APP | |
| SCHEMBL9317157 | 0.86 | POLB (0.40) | TSHRALDH1A1PTGS1HSD17B3APP | |
| SCHEMBL9317886 | 0.85 | MMP13 (0.47) | TSHRALDH1A1CYP3A4HPGDHDAC1 | |
| SCHEMBL9317883 | 0.85 | MMP13 (0.47) | TSHRALDH1A1CYP3A4HPGDHDAC1 | |
| SCHEMBL9318829 | 0.85 | TSHR (0.35) | TSHRALDH1A1CYP3A4APPHPGD | |
| SCHEMBL9318819 | 0.85 | TSHR (0.35) | TSHRALDH1A1CYP3A4APPHPGD | |
| SCHEMBL9317336 | 0.84 | ALDH1A1 (0.42) | TSHRALDH1A1CYP3A4APPHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5322986-A | Methods for preparing polymer stripe waveguides and polymer stripe waveguides prepared thereby | EASTMAN KODAK COMPANY (US) | 1994-06-21 | — | — | US | disclosed |
| US-5157541-A | Support with dielectric, reflection metal, polymeric electrooptical layers, couterelectrode | EASTMAN KODAK COMPANY (US) | 1992-10-20 | — | — | US | disclosed |
| US-5075796-A | OPTICAL ARTICLE FOR MULTICOLOR IMAGING | EASTMAN KODAK COMPANY (US) | 1991-12-24 | — | — | US | disclosed |
| US-4948225-A | REFLECTIVE METAL LAYER, DIELECTRICS, PROTECTIVE COATING | EASTMAN KODAK COMPANY (US) | 1990-08-14 | — | — | US | disclosed |