SCHEMBL9317883

SCHEMBL9317883

C=CC(=O)OCCCCCCS(=O)(=O)c1ccc(/C=C/c2ccc(OC)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP13 P45452 3/20 0.47
MMP8 P22894 1/20 0.47
LMNA P02545 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
MMP1 P03956 3/20 0.46
HTT P42858 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
PPARA Q07869 2/20 0.46
FFAR1 O14842 1/20 0.46
PPARG P37231 1/20 0.46
PPARD Q03181 1/20 0.46
TDP1 Q9NUW8 1/20 0.44
TSHR P16473 2/20 0.43
ALDH1A1 P00352 1/20 0.43
CYP3A4 P08684 1/20 0.43
HDAC3 O15379 1/20 0.42
STAT3 P40763 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9317886 1.00 MMP13 (0.47) MMP13MMP8LMNASMN1; SMN2MMP1
SCHEMBL9317794 0.88 MMP13 (0.46) MMP13MMP8LMNASMN1; SMN2MMP1
SCHEMBL9317783 0.88 MMP13 (0.46) MMP13MMP8LMNASMN1; SMN2MMP1
SCHEMBL9100502 0.86 MMP1 (0.51) MMP1TSHRHPGD
SCHEMBL9317336 0.85 ALDH1A1 (0.42) LMNANPSR1TSHRALDH1A1CYP3A4
SCHEMBL9317409 0.85 TSHR (0.42) LMNASMN1; SMN2TSHRALDH1A1CYP3A4
SCHEMBL9317332 0.85 ALDH1A1 (0.42) LMNANPSR1TSHRALDH1A1CYP3A4
SCHEMBL9318781 0.85 HTT (0.46) MMP13MMP8LMNASMN1; SMN2MMP1
SCHEMBL9317414 0.85 TSHR (0.42) LMNASMN1; SMN2TSHRALDH1A1CYP3A4
SCHEMBL9318784 0.85 HTT (0.46) MMP13MMP8LMNASMN1; SMN2MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5322986-A Methods for preparing polymer stripe waveguides and polymer stripe waveguides prepared thereby EASTMAN KODAK COMPANY (US) 1994-06-21 US disclosed
US-5157541-A Support with dielectric, reflection metal, polymeric electrooptical layers, couterelectrode EASTMAN KODAK COMPANY (US) 1992-10-20 US disclosed
US-5075796-A OPTICAL ARTICLE FOR MULTICOLOR IMAGING EASTMAN KODAK COMPANY (US) 1991-12-24 US disclosed
US-4948225-A REFLECTIVE METAL LAYER, DIELECTRICS, PROTECTIVE COATING EASTMAN KODAK COMPANY (US) 1990-08-14 US disclosed