SCHEMBL9317416

SCHEMBL9317416

C=CC(=O)OCCCCCCS(=O)(=O)c1ccc(N=Nc2ccc(OC[C@H](C)CC)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 2/20 0.37
TSHR P16473 2/20 0.36
HPGD P15428 1/20 0.36
ALDH1A1 P00352 2/20 0.36
CYP3A4 P08684 1/20 0.36
FFAR1 O14842 1/20 0.35
THRB P10828 2/20 0.35
GPR88 Q9GZN0 4/20 0.33
MMP3 P08254 1/20 0.32
CTDSP1 Q9GZU7 1/20 0.32
PLA2G2C Q5R387 1/20 0.32
CYP1A2 P05177 1/20 0.32
HTT P42858 2/20 0.32
MMP13 P45452 2/20 0.31
PPARA Q07869 1/20 0.31
PLA2G4B P0C869 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
ADAM17 P78536 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9317422 1.00 MMP1 (0.37) MMP1TSHRHPGDALDH1A1CYP3A4
SCHEMBL9317418 0.90 MMP1 (0.40) MMP1TSHRHPGDALDH1A1CYP3A4
SCHEMBL9317444 0.87 THRB (0.39) MMP1TSHRHPGDALDH1A1CYP3A4
SCHEMBL9317448 0.87 THRB (0.39) MMP1TSHRHPGDALDH1A1CYP3A4
SCHEMBL9317105 0.87 HTT (0.45) MMP1TSHRALDH1A1FFAR1GPR88
SCHEMBL9317399 0.84 TSHR (0.35) TSHRHPGDALDH1A1CYP3A4THRB
SCHEMBL9317393 0.84 TSHR (0.35) TSHRHPGDALDH1A1CYP3A4THRB
SCHEMBL9317794 0.84 MMP13 (0.46) MMP1TSHRHPGDALDH1A1CYP3A4
SCHEMBL9317783 0.84 MMP13 (0.46) MMP1TSHRHPGDALDH1A1CYP3A4
SCHEMBL9318770 0.83 TSHR (0.34) TSHRHPGDALDH1A1CYP3A4THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5322986-A Methods for preparing polymer stripe waveguides and polymer stripe waveguides prepared thereby EASTMAN KODAK COMPANY (US) 1994-06-21 US disclosed
US-5157541-A Support with dielectric, reflection metal, polymeric electrooptical layers, couterelectrode EASTMAN KODAK COMPANY (US) 1992-10-20 US disclosed
US-5075796-A OPTICAL ARTICLE FOR MULTICOLOR IMAGING EASTMAN KODAK COMPANY (US) 1991-12-24 US disclosed
EP-0422725-A2 High x(2) optical article EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
EP-0422723-A2 Optical article for reflection modulation EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
US-4948225-A REFLECTIVE METAL LAYER, DIELECTRICS, PROTECTIVE COATING EASTMAN KODAK COMPANY (US) 1990-08-14 US disclosed