SCHEMBL9317485

SCHEMBL9317485

C=CC(=O)OCCOc1ccc(/C=C/c2ccc(S(=O)(=O)CC(C)CC)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.47
PTPN1 P18031 2/20 0.39
PTGS1 P23219 1/20 0.39
PTGS2 P35354 1/20 0.39
MMP1 P03956 2/20 0.38
MMP13 P45452 2/20 0.38
AOC2 O75106 1/20 0.38
LMNA P02545 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MMP3 P08254 2/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35
AHR P35869 1/20 0.35
GAA P10253 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9317490 1.00 THRB (0.47) THRBPTPN1PTGS1PTGS2MMP1
SCHEMBL9317440 0.94 ALB (0.40) THRBPTPN1PTGS1PTGS2MMP1
SCHEMBL9317122 0.88 THRB (0.46) THRBMMP1MMP13AOC2HPGD
SCHEMBL9317109 0.88 THRB (0.46) THRBMMP1MMP13AOC2HPGD
SCHEMBL9317116 0.88 THRB (0.46) THRBMMP1MMP13AOC2HPGD
SCHEMBL9318847 0.86 POLB (0.41) THRBPTPN1PTGS1PTGS2MMP1
SCHEMBL9318842 0.86 POLB (0.41) THRBPTPN1PTGS1PTGS2MMP1
SCHEMBL9318799 0.84 ALDH1A1 (0.34) THRBMMP1MMP13LMNATDP1
SCHEMBL9318806 0.84 ALDH1A1 (0.34) THRBMMP1MMP13LMNATDP1
SCHEMBL9317316 0.82 ALDH1A1 (0.38) THRBMMP1MMP13AOC2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5322986-A Methods for preparing polymer stripe waveguides and polymer stripe waveguides prepared thereby EASTMAN KODAK COMPANY (US) 1994-06-21 US disclosed
US-5157541-A Support with dielectric, reflection metal, polymeric electrooptical layers, couterelectrode EASTMAN KODAK COMPANY (US) 1992-10-20 US disclosed
US-5075796-A OPTICAL ARTICLE FOR MULTICOLOR IMAGING EASTMAN KODAK COMPANY (US) 1991-12-24 US disclosed
US-4948225-A REFLECTIVE METAL LAYER, DIELECTRICS, PROTECTIVE COATING EASTMAN KODAK COMPANY (US) 1990-08-14 US disclosed