Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | PPID | Q08752 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4619371 | 0.87 | SMN1; SMN2 (0.54) | SMN1; SMN2POLBPPIDALDH1A1MEN1 | |
| SCHEMBL18106113 | 0.82 | ALDH1A1 (0.50) | SMN1; SMN2POLBPPIDALDH1A1MEN1 | |
| SCHEMBL18095613 | 0.82 | ALDH1A1 (0.50) | SMN1; SMN2POLBPPIDALDH1A1MEN1 | |
| SCHEMBL18106124 | 0.82 | ALDH1A1 (0.50) | SMN1; SMN2POLBPPIDALDH1A1MEN1 | |
| SCHEMBL9716850 | 0.78 | SMN1; SMN2 (0.58) | SMN1; SMN2POLBPPIDALDH1A1MEN1 | |
| SCHEMBL27511978 | 0.77 | MAPT (0.46) | SMN1; SMN2POLBPPIDALDH1A1GAA | |
| SCHEMBL28490145 | 0.77 | CYP2C19 (0.48) | SMN1; SMN2ALDH1A1KMT2ATSHR | |
| SCHEMBL21447568 | 0.77 | HSD11B1 (0.52) | SMN1; SMN2POLBPPIDALDH1A1MEN1 | |
| SCHEMBL15688271 | 0.77 | KIF11 (0.45) | SMN1; SMN2POLBPPIDALDH1A1 | |
| SCHEMBL313012 | 0.76 | POLB (0.55) | SMN1; SMN2POLBPPIDALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5278326-A | Aromatic | WARNER-LAMBERT COMPANY (US) | 1994-01-11 | — | — | US | disclosed |