Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28931087 | 0.92 | ACHE (0.61) | ACHETSHRLMNAALOX12NPSR1 | |
| SCHEMBL13169377 | 0.84 | ACHE (0.35) | ACHETSHRLMNAALOX12NPSR1 | |
| SCHEMBL28040349 | 0.82 | ACHE (0.43) | ACHETSHRLMNAALOX12NPSR1 | |
| SCHEMBL2454184 | 0.81 | ACHE (0.42) | ACHETSHRLMNAALOX12NPSR1 | |
| SCHEMBL52125 | 0.78 | TSHR (0.44) | ACHETSHRLMNAALOX12ALDH1A1 | |
| SCHEMBL28278745 | 0.78 | TSHR (0.44) | ACHETSHRLMNAALOX12ALDH1A1 | |
| SCHEMBL26864158 | 0.77 | MAOA (0.48) | LMNAALOX12ALDH1A1HPGDCYP3A4 | |
| SCHEMBL1556125 | 0.77 | — | — | |
| SCHEMBL9318204 | 0.76 | ACHE (0.56) | ACHETSHRLMNAALOX12ALDH1A1 | |
| Chloromethane SCHEMBL28762557 | 0.75 | TSHR (0.44) | ACHETSHRLMNAALOX12NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314327-B1 | Method of producing polysilane compounds | MITSUI PETROCHEMICAL IND (JP) | 1994-01-05 | — | — | EP | disclosed |
| US-5089648-A | Using tetrakis/triethylphosphine/nickel polymerization catalyst | ETHYL CORPORATION (US) | 1992-02-18 | — | — | US | disclosed |
| US-5089646-A | Polysilane precursors | ETHYL CORPORATION (US) | 1992-02-18 | — | — | US | disclosed |
| US-5047569-A | POLYMERIZING MONOMERIC OR PRECURSOR IN PRESENCE OF A DIPHOSPHOROUS NICKEL CHLORIDE CATALYSST | ETHYL CORPORATION (US) | 1991-09-10 | — | — | US | disclosed |
| US-5003100-A | Polysilanes and their formation using rhodium dimer catalyst | ETHYL CORPORATION (US) | 1991-03-26 | — | — | US | disclosed |
| US-4900861-A | POLYMERIZING A SILANE HAVING 2 OR 3 HYDROGENS ATTACHED USING A CATALYTIC ORGANOMETALLIC COMPLEX OF NICKEL, COBALT, RUTHENIUM, PALLADIUM OR IRIDIUM | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1990-02-13 | — | — | US | disclosed |
| EP-0314327-A2 | Method of producing polysilane compounds | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-05-03 | — | — | EP | disclosed |