Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.71 |
| ▸ | PGR | P06401 | 2/20 | 0.71 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | PDE4A | P27815 | 1/20 | 0.71 |
| ▸ | HRH1 | P35367 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.71 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.71 |
| ▸ | NPC1 | O15118 | 5/20 | 0.69 |
| ▸ | RAB9A | P51151 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 6/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30374771 | 1.00 | HPGD (0.71) | HPGDALDH1A1LMNAMAPK1CYP1A2 | |
| SCHEMBL29415029 | 0.93 | LMNA (0.81) | HPGDALDH1A1LMNAMAPK1CYP1A2 | |
| SCHEMBL228916 | 0.93 | LMNA (0.81) | HPGDALDH1A1LMNAMAPK1CYP1A2 | |
| SCHEMBL6171166 | 0.92 | HPGD (0.79) | HPGDALDH1A1LMNAMAPK1CYP1A2 | |
| Oxybenzone SCHEMBL1954205 | 0.89 | HPGD (0.91) | HPGDALDH1A1LMNAMAPK1CYP1A2 | |
| SCHEMBL30900821 | 0.88 | NPC1 (0.89) | HPGDALDH1A1LMNAMAPK1CYP1A2 | |
| SCHEMBL1348833 | 0.88 | NPC1 (0.89) | HPGDALDH1A1LMNAMAPK1CYP1A2 | |
| SCHEMBL29419872 | 0.88 | NPC1 (0.89) | HPGDALDH1A1LMNAMAPK1CYP1A2 | |
| SCHEMBL93206 | 0.88 | NPC1 (0.89) | HPGDALDH1A1LMNAMAPK1CYP1A2 | |
| 2,4-Dihydroxybenzophenone SCHEMBL18279847 | 0.88 | HPGD (0.88) | HPGDALDH1A1LMNAMAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4557730-A | Solutions of U.V. absorbers useful for improving the light fastness of dyeings on polyester | SANDOZ LTD. (CH) | 1985-12-10 | — | — | US | claimed |
| US-20260062580-A1 | REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT | THE PILOT INK CO., LTD. (JP) | 2026-03-05 | — | — | US | disclosed |
| EP-3954745-B1 | REVERSIBLY THERMOCHROMIC AQUEOUS INK COMPOSITION FOR WRITING UTENSILS, AND REFILL AND WATER-BASED BALLPOINT PEN EACH INTERNALLY CONTAINING SAME | KK PILOT CORPORATION ALSO TRADING AS PILOT CORPORATION (JP) | 2026-01-07 | — | — | EP | disclosed |
| US-12460099-B2 | Reversibly thermochromic composition, reversibly thermochromic microcapsule pigment encapsulating reversibly thermochromic composition, and writing instrument using reversibly thermochromic microcapsule pigment | THE PILOT INK CO., LTD. (JP) | 2025-11-04 | — | — | US | disclosed |
| US-12421411-B2 | Aqueous ink composition for reversibly thermochromic writing instrument, and refill and aqueous ballpoint pen incorporating aqueous ink composition for reversibly thermochromic writing instrument | KABUSHIKI KAISHA PILOT CORPORATION (JP) | 2025-09-23 | — | — | US | disclosed |
| CN-113646052-B | Reversible thermochromic composition, reversible thermochromic microcapsule pigment, and writing instrument | 百乐墨水株式会社 | 2024-05-17 | — | — | CN | disclosed |
| CN-113785023-B | Water-based ink composition for reversible thermochromic writing instrument, refill for refill and water-based ballpoint pen incorporating same | 株式会社百乐 | 2023-05-12 | — | — | CN | disclosed |
| US-20230018132-A1 | REVERSIBLY THERMOCHROMIC AQUEOUS INKJET PRINTER INK COMPOSITION, INKJET PRINTER AND INK CARTRIDGE USING THE SAME | RISO TECHNOLOGIES CORPORATION (JP) | 2023-01-19 | — | — | US | disclosed |
| US-20220251406-A1 | AQUEOUS INK COMPOSITION FOR REVERSIBLY THERMOCHROMIC WRITING INSTRUMENT, AND REFILL AND AQUEOUS BALLPOINT PEN INCORPORATING AQUEOUS INK COMPOSITION FOR REVERSIBLY THERMOCHROMIC WRITING INSTRUMENT | KABUSHIKI KAISHA PILOT CORPORATION (ALSO TRADING AS PILOT CORPORATION) (JP) | 2022-08-11 | — | — | US | disclosed |
| US-20220169919-A1 | REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT | THE PILOT INK CO., LTD. (JP) | 2022-06-02 | — | — | US | disclosed |
| EP-1577288-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | Eisai Co., Ltd. (JP) | 2005-09-21 | — | — | EP | disclosed |
| US-6638620-B2 | Discoloration sensitivity | THE PILOT INK CO., LTD. (JP) | 2003-10-28 | — | — | US | disclosed |
| EP-1179435-A1 | Reversible thermochromic composition having improved light-fastness and product comprising same | The Pilot Ink Co., Ltd. (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-0442068-B1 | Benzophenone derivatives and polymers containing phenolic hydroxyl groups | BAYER AG (DE) | 1994-06-08 | — | — | EP | disclosed |
| EP-0228020-B1 | POLY(PHENYLENE ETHER)-BOUND UV ABSORBER | GENERAL ELECTRIC COMPANY (US) | 1992-07-01 | — | — | EP | disclosed |
| EP-0442068-A2 | Benzophenone derivatives and polymers containing phenolic hydroxyl groups | BAYER AG (DE) | 1991-08-21 | — | — | EP | disclosed |
| US-4668739-A | BENZOPHENONE DERIVATIVE, THERMOPLASTIC BLENDS | GENERAL ELECTRIC COMPANY (US) | 1987-05-26 | — | — | US | disclosed |
| US-4557730-A | Solutions of U.V. absorbers useful for improving the light fastness of dyeings on polyester | SANDOZ LTD. (CH) | 1985-12-10 | — | — | US | disclosed |
| US-4362895-A | Ultraviolet absorbing copolymers | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1982-12-07 | — | — | US | disclosed |
| US-4310650-A | Ultraviolet absorbing copolymers | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1982-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260062580-A1 | REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT | TYR, SCO2, HBB | HPGD 3663/4885ALDH1A1 3835/4885LMNA 1365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.