Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.41 |
| ▸ | ADH1B | P00325 | 1/20 | 0.41 |
| ▸ | ADH1C | P00326 | 1/20 | 0.41 |
| ▸ | ADH1A | P07327 | 1/20 | 0.41 |
| ▸ | ADH7 | P40394 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | GLS | O94925 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853013 | 0.79 | KCNN4 (0.41) | KCNN4ADH1BADH1CADH1AADH7 | |
| SCHEMBL27948873 | 0.77 | KCNN4 (0.61) | KCNN4NR3C2TAAR1LMNAHTT | |
| SCHEMBL28778295 | 0.74 | CYP2C19 (0.46) | KCNN4KMT2AALDH1A1LMNAHTT | |
| SCHEMBL5965957 | 0.72 | TAAR1 (0.47) | KCNN4ADH1BADH1CADH1AADH7 | |
| SCHEMBL13171304 | 0.70 | KIF11 (0.60) | KCNN4TAAR1KIF11 | |
| SCHEMBL9318575 | 0.70 | KCNN4 (0.44) | KCNN4TAAR1ALDH1A1LMNAKIF11 | |
| SCHEMBL7959485 | 0.70 | MAPT (0.43) | KCNN4KMT2ALMNAHTTL3MBTL1 | |
| SCHEMBL28262161 | 0.69 | KCNN4 (0.45) | KCNN4NR3C2KMT2ATAAR1KIF11 | |
| SCHEMBL9853003 | 0.68 | KCNN4 (0.41) | KCNN4NR3C2TAAR1ALDH1A1LMNA | |
| SCHEMBL28397743 | 0.68 | CYP2C19 (0.42) | KCNN4MEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593557-A1 | AROMATIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY. | MERCK SHARP & DOHME (GB) | 1994-04-27 | — | — | EP | claimed |