Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | BID | P55957 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7526622 | 0.88 | CA2 (0.53) | TSHRALDH1A1TDP1HTR1ATYR | |
| SCHEMBL31243576 | 0.84 | BID (0.47) | TYRBIDMCL1BCL2L1BAK1 | |
| SCHEMBL6706198 | 0.83 | TSHR (0.58) | TSHRALDH1A1TDP1HTR1ATYR | |
| SCHEMBL10984997 | 0.82 | TSHR (0.56) | TSHRALDH1A1TDP1HTR1ATYR | |
| SCHEMBL5707464 | 0.82 | TSHR (0.56) | TSHRALDH1A1TDP1HTR1ATYR | |
| Ethyne SCHEMBL4194758 | 0.81 | HTR1A (0.56) | TSHRTDP1HTR1ATYRBID | |
| Propane SCHEMBL2457613 | 0.81 | ALDH1A1 (0.56) | TSHRALDH1A1TDP1TYRCYP3A4 | |
| SCHEMBL20232 | 0.80 | HTR1A (0.60) | TSHRTDP1HTR1ATYRBID | |
| SCHEMBL29450060 | 0.80 | HTR1A (0.60) | TSHRTDP1HTR1ATYRBID | |
| SCHEMBL9319489 | 0.80 | HTR1A (0.60) | TSHRTDP1HTR1ATYRBID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H1388-H | Metathesis polymerizable olefin monomer, procatalyst, procatalyst activator, and at least one of lewis acid catlayst , anionic catalyst, free radical initiator and hydrosilation catalyst | HERCULES INCORPORATED (US) | 1994-12-06 | — | — | US | disclosed |