Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.51 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 4/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7358608 | 0.92 | ITGB3 (0.57) | ITGB3ITGA2BPRMT5WDR77APP | |
| SCHEMBL9317817 | 0.90 | ITGB3 (0.51) | ITGB3ITGA2BPRMT5WDR77MAPT | |
| Acetic Acid SCHEMBL9318257 | 0.89 | ITGB3 (0.62) | ITGB3ITGA2BPRMT5WDR77USP2 | |
| SCHEMBL9317712 | 0.82 | ITGB3 (0.57) | ITGB3ITGA2BPRMT5WDR77F10 | |
| Acetic Acid SCHEMBL9317585 | 0.81 | ITGB3 (0.57) | ITGB3ITGA2BPRMT5WDR77F10 | |
| Acetic Acid SCHEMBL7358601 | 0.81 | ITGB3 (0.70) | ITGB3ITGA2BPRMT5WDR77 | |
| SCHEMBL7334232 | 0.80 | ITGB3 (0.45) | ITGB3ITGA2BPRMT5WDR77LMNA | |
| SCHEMBL7329437 | 0.80 | ITGB3 (0.45) | ITGB3ITGA2BMAPTLMNA | |
| SCHEMBL9319480 | 0.80 | ITGB3 (0.45) | ITGB3ITGA2BPRMT5WDR77 | |
| SCHEMBL7330253 | 0.80 | ITGB3 (0.49) | ITGB3ITGA2BF10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610334-A1 | NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPII b?III a? RECEPTOR. | GENENTECH INC (US) | 1994-08-17 | — | — | EP | disclosed |