Malonic Acid

Malonic Acid

SCHEMBL9318328

O=C(O)CC(=O)O.O=C(O)CC(=O)O.O=C(O)CC(=O)O.O=C(O)CC(=O)O.c1ccoc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.53
SRR Q9GZT4 1/20 0.53
MAPK1 P28482 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
CYP2C19 P33261 2/20 0.36
TSHR P16473 1/20 0.36
FFAR1 O14842 1/20 0.32
CYP2D6 P10635 2/20 0.32
HIF1A Q16665 1/20 0.32
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
CES1 P23141 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
AKR1B1 P15121 1/20 0.31
ERCC5 P28715 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetoacetic Acid SCHEMBL28186064 0.85 KDM4E (0.39) LDHASRRMAPK1TDP1CYP2C19
Glycolic Acid SCHEMBL6040104 0.82 MAPK1 (0.47) LDHASRRMAPK1TDP1CYP2C19
Succinic Acid SCHEMBL18329309 0.82 LMNA (0.53) MAPK1TDP1CYP2C19TSHRFFAR1
Succinic Acid SCHEMBL28022052 0.82 LMNA (0.53) MAPK1TDP1CYP2C19TSHRFFAR1
Furan SCHEMBL27656052 0.81 MAPK1 (0.61) MAPK1TDP1
Furan SCHEMBL5278070 0.81 MAPK1 (0.61) MAPK1TDP1
Furan SCHEMBL7296766 0.81
Malonic Acid SCHEMBL28935459 0.80 LDHA (0.82) LDHASRRMAPK1TDP1CYP2C19
Propionic Acid SCHEMBL627391 0.80 FFAR3 (0.56) MAPK1TDP1CYP2C19FFAR1CYP2D6
Propionic Acid SCHEMBL28319886 0.80 FFAR3 (0.56) MAPK1TDP1CYP2C19FFAR1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0447967-B1 Gelation of acrylamide-containing polymers with furfuryl alcohol and water dispersible aldehydes PHILLIPS PETROLEUM CO (US) 1994-05-18 EP claimed
EP-0447967-A2 Gelation of acrylamide-containing polymers with furfuryl alcohol and water dispersible aldehydes PHILLIPS PETROLEUM COMPANY (US) 1991-09-25 EP claimed
US-5043364-A Adjusting permeability of well bores PHILLIPS PETROLEUM COMPANY (US) 1991-08-27 US claimed
EP-0447967-B1 Gelation of acrylamide-containing polymers with furfuryl alcohol and water dispersible aldehydes PHILLIPS PETROLEUM CO (US) 1994-05-18 EP disclosed
EP-0447967-A2 Gelation of acrylamide-containing polymers with furfuryl alcohol and water dispersible aldehydes PHILLIPS PETROLEUM COMPANY (US) 1991-09-25 EP disclosed
US-5043364-A Adjusting permeability of well bores PHILLIPS PETROLEUM COMPANY (US) 1991-08-27 US disclosed