Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | HNF4A | P41235 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9318355 | 0.75 | RXRA (0.41) | POLBRXRAHNF4ATDP1 | |
| SCHEMBL9483500 | 0.63 | RXRA (0.42) | POLBRXRAHNF4A | |
| SCHEMBL9484572 | 0.63 | POLB (0.52) | POLBL3MBTL1MEN1KMT2ARXRA | |
| SCHEMBL11249732 | 0.61 | LMNA (0.51) | POLBLMNAALDH1A1MAPTKDM4E | |
| SCHEMBL9379226 | 0.61 | KMT2A (0.51) | POLBLMNAALDH1A1MAPTPTPN2 | |
| SCHEMBL5665343 | 0.61 | POLB (0.46) | POLBLMNAALDH1A1MAPTCYP1A2 | |
| SCHEMBL16800062 | 0.60 | POLB (0.62) | POLBLMNAALDH1A1MAPTKDM4E | |
| SCHEMBL16513211 | 0.59 | POLB (0.44) | POLBLMNAALDH1A1MAPTPTPN2 | |
| SCHEMBL9019972 | 0.59 | CA12 (0.49) | POLBLMNAALDH1A1MAPTPTPN2 | |
| SCHEMBL8582885 | 0.58 | CA12 (0.51) | POLBLMNAALDH1A1MAPTPTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382078-B1 | AROMATIC KETO COMPOUNDS, THEIR PREPARATION AND MEDICINAL AS WELL AS COSMETIC PREPARATIONS CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1993-09-22 | — | — | EP | disclosed |
| EP-0382078-A1 | Aromatic keto compounds, their preparation and medicinal as well as cosmetic preparations containing them | BASF Aktiengesellschaft (DE) | 1990-08-16 | — | — | EP | disclosed |