Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 10/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA6 | P23280 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 5/20 | 0.49 |
| ▸ | RARG | P13631 | 5/20 | 0.49 |
| ▸ | RARA | P10276 | 4/20 | 0.49 |
| ▸ | RXRB | P28702 | 7/20 | 0.48 |
| ▸ | RXRG | P48443 | 5/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | HNF4A | P41235 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9722089 | 0.88 | LMNA (0.50) | RXRARARBRARGRARARXRB | |
| SCHEMBL9318566 | 0.86 | RXRA (0.44) | RXRAPKMRARBRARGRARA | |
| SCHEMBL20762771 | 0.80 | CA12 (0.56) | RXRACA12CA1CA2CA4 | |
| SCHEMBL7154575 | 0.78 | RXRA (0.52) | RXRARARBRARGRARARXRB | |
| SCHEMBL11213073 | 0.75 | LMNA (0.50) | RXRACA12CA1CA2CA4 | |
| SCHEMBL9217192 | 0.75 | ACHE (0.42) | RXRARARBRARGRARARXRB | |
| SCHEMBL9510915 | 0.75 | RXRA (0.39) | RXRARARBRARGRARARXRB | |
| SCHEMBL9319764 | 0.75 | CYP3A4 (0.51) | RXRARARBRARGRARACYP26A1 | |
| SCHEMBL5846230 | 0.74 | RARG (0.62) | RXRARARBRARGRARA | |
| SCHEMBL27054971 | 0.73 | RXRA (0.36) | RXRARARBRARGRARARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326900-A | Aromatic keto compounds, the preparation thereof, and drugs and cosmetics containing these | BASF AKTIENGESELLSCHAFT (DE) | 1994-07-05 | — | — | US | disclosed |
| EP-0382078-B1 | AROMATIC KETO COMPOUNDS, THEIR PREPARATION AND MEDICINAL AS WELL AS COSMETIC PREPARATIONS CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1993-09-22 | — | — | EP | disclosed |
| US-5194664-A | Aromatic keto compounds, the preparation thereof, and drugs and cosmetics containing these | BASF AKTIENGESELLSCHAFT (DE) | 1993-03-16 | — | — | US | disclosed |
| EP-0382078-A1 | Aromatic keto compounds, their preparation and medicinal as well as cosmetic preparations containing them | BASF Aktiengesellschaft (DE) | 1990-08-16 | — | — | EP | disclosed |