SCHEMBL9318562

SCHEMBL9318562

C=C(C)C(=O)OCCCCCCN(C)c1ccc(/C=C/c2ccc(S(C)(=O)=O)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
HTT P42858 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
TSHR P16473 2/20 0.39
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
MAOB P27338 2/20 0.34
MAOA P21397 1/20 0.34
BCHE P06276 2/20 0.33
ACHE P22303 2/20 0.33
GSR P00390 2/20 0.33
FLT3 P36888 1/20 0.33
LMNA P02545 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9318568 1.00 POLB (0.40) POLBAPEX1HTTTDP1TSHR
SCHEMBL9846841 0.91 MAOB (0.36) POLBMEN1KMT2AMAOBGSR
SCHEMBL9656351 0.90 POLB (0.40) POLBAPEX1HTTTDP1TSHR
SCHEMBL9317170 0.89 POLB (0.40) POLBAPEX1HTTTDP1TSHR
SCHEMBL9317175 0.89 POLB (0.40) POLBAPEX1HTTTDP1TSHR
SCHEMBL9551568 0.87 MMP14 (0.41) POLBAPEX1HTTTDP1TSHR
SCHEMBL9551567 0.87 MMP14 (0.41) POLBAPEX1HTTTDP1TSHR
SCHEMBL9317854 0.86 TSHR (0.41) POLBTSHRMEN1KMT2AMAOB
SCHEMBL9317849 0.86 TSHR (0.41) POLBTSHRMEN1KMT2AMAOB
SCHEMBL9804507 0.84 SMN1; SMN2 (0.43) POLBAPEX1HTTTDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5322986-A Methods for preparing polymer stripe waveguides and polymer stripe waveguides prepared thereby EASTMAN KODAK COMPANY (US) 1994-06-21 US disclosed
US-5157541-A Support with dielectric, reflection metal, polymeric electrooptical layers, couterelectrode EASTMAN KODAK COMPANY (US) 1992-10-20 US disclosed
US-5075796-A OPTICAL ARTICLE FOR MULTICOLOR IMAGING EASTMAN KODAK COMPANY (US) 1991-12-24 US disclosed
EP-0422725-A2 High x(2) optical article EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
EP-0422723-A2 Optical article for reflection modulation EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
US-4948225-A REFLECTIVE METAL LAYER, DIELECTRICS, PROTECTIVE COATING EASTMAN KODAK COMPANY (US) 1990-08-14 US disclosed