SCHEMBL9317170

SCHEMBL9317170

C=C(C)C(=O)OCCCCCCN(C)c1ccc(/C=C/c2ccc(S(=O)(=O)c3ccccc3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
HTT P42858 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TSHR P16473 2/20 0.37
CTDSP1 Q9GZU7 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
BCHE P06276 3/20 0.36
ACHE P22303 3/20 0.36
MAOB P27338 4/20 0.35
ALDH1A1 P00352 2/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MAOA P21397 2/20 0.34
CACNA1B Q00975 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9317175 1.00 POLB (0.40) POLBAPEX1HTTTDP1MEN1
SCHEMBL9317586 0.92 CTDSP1 (0.39) POLBAPEX1HTTTDP1MEN1
SCHEMBL9317582 0.92 CTDSP1 (0.39) POLBAPEX1HTTTDP1MEN1
SCHEMBL9318562 0.89 POLB (0.40) POLBAPEX1HTTTDP1MEN1
SCHEMBL9318568 0.89 POLB (0.40) POLBAPEX1HTTTDP1MEN1
SCHEMBL9317009 0.88 MMP14 (0.41) POLBAPEX1HTTTDP1MEN1
SCHEMBL9317012 0.88 MMP14 (0.41) POLBAPEX1HTTTDP1MEN1
SCHEMBL9317451 0.87 ALDH1A1 (0.39) MEN1KMT2ATSHRCTDSP1HDAC1
SCHEMBL9317458 0.87 ALDH1A1 (0.39) MEN1KMT2ATSHRCTDSP1HDAC1
SCHEMBL9317020 0.84 POLB (0.58) POLBAPEX1HTTTDP1HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5322986-A Methods for preparing polymer stripe waveguides and polymer stripe waveguides prepared thereby EASTMAN KODAK COMPANY (US) 1994-06-21 US disclosed
US-5157541-A Support with dielectric, reflection metal, polymeric electrooptical layers, couterelectrode EASTMAN KODAK COMPANY (US) 1992-10-20 US disclosed
US-5075796-A OPTICAL ARTICLE FOR MULTICOLOR IMAGING EASTMAN KODAK COMPANY (US) 1991-12-24 US disclosed
EP-0422725-A2 High x(2) optical article EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
EP-0422723-A2 Optical article for reflection modulation EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
US-4948225-A REFLECTIVE METAL LAYER, DIELECTRICS, PROTECTIVE COATING EASTMAN KODAK COMPANY (US) 1990-08-14 US disclosed