Phosphoric Acid

SCHEMBL9318697

COc1cccc(C[P+](c2cccc(C)c2)(c2cccc(C)c2)c2cccc(C)c2)c1.COc1cccc(C[P+](c2ccccc2C)(c2ccccc2C)c2ccccc2C)c1.COc1cccc(C[P+](c2ccccc2C)(c2ccccc2C)c2ccccc2C)c1.COc1cccc(C[P+](c2ccccc2C)(c2ccccc2C)c2ccccc2C)c1.O=P([O-])([O-])[O-].[Cl-]

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA1A ADRA1B ADRA1D ADRB1 ADRB2 ADRB3 CYP11B1 DPP4 FGFR1 FGFR2 FGFR3 FGFR4 HRH1 JAK1 JAK2 JAK3 KCNA1 KCNA10 KCNA2 KCNA3 KCNA4 KCNA5 KCNA6 KCNA7 KCNB1 KCNB2 KCNC1 KCNC2 KCNC3 KCNC4 KCND1 KCND2 KCND3 KCNF1 KCNG1 KCNG2 KCNG3 KCNG4 KCNH1 KCNH2 KCNH3 KCNH4 KCNH5 KCNH6 KCNH7 KCNH8 KCNQ1 KCNQ2 KCNQ3 KCNQ4 KCNQ5 KCNS1 KCNS2 KCNS3 KCNV1 KCNV2 KDR KIT NA OPRD1 OPRK1 OPRM1 P PDGFRB PIK3CD SCN10A SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SMO TYK2 pol rplA rplB rplC rplD rplE rplF rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmC rpmD rpmE rpmF rpmG rpmH rpmI rpmJ rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsS rpsT rpsU ykgM ykgO

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 17)

	gene	UniProt	supporting neighbours	confidence
▸	SCN8A known ✓	Q9UQD0	1/20	0.36

▸	MAOB	P27338	1/20	0.39

▸	TAAR1	Q96RJ0	3/20	0.39

▸	ACHE	P22303	1/20	0.38

▸	ATM	Q13315	1/20	0.36

▸	LMNA	P02545	2/20	0.36

▸	MAPT	P10636	1/20	0.36

▸	HTT	P42858	1/20	0.36

▸	IDH1	O75874	1/20	0.35

▸	TP53	P04637	1/20	0.35

▸	HSD17B2	P37059	1/20	0.35

▸	CMA1	P23946	1/20	0.34

▸	MMP13	P45452	2/20	0.34

▸	MEN1	O00255	1/20	0.34

▸	KMT2A	Q03164	1/20	0.34

▸	IDO1	P14902	1/20	0.34

▸	AGXT	P21549	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Phosphoric Acid SCHEMBL9318706	0.97	MAOB (0.38)	MAOBTAAR1ACHEATMLMNA
Phosphoric Acid SCHEMBL7197200	0.91	TAAR1 (0.46)	MAOBTAAR1SCN8AATMIDH1
Phosphoric Acid SCHEMBL7197782	0.90	ACHE (0.47)	MAOBTAAR1ACHEIDH1HSD17B2
Phosphoric Acid SCHEMBL9318089	0.86	MAOB (0.42)	MAOBTAAR1ACHELMNAMAPT
Hydrochloric Acid SCHEMBL7195761	0.85	TAAR1 (0.51)	MAOBTAAR1SCN8AMAPTIDH1
Hydrochloric Acid SCHEMBL7195803	0.83	ACHE (0.55)	MAOBTAAR1ACHEHSD17B2CMA1
Phosphoric Acid SCHEMBL9318099	0.83	MMP13 (0.43)	MAOBTAAR1ACHELMNAMAPT
Iodide SCHEMBL7197231	0.82	TAAR1 (0.51)	MAOBTAAR1SCN8AMAPTIDH1
Bromide SCHEMBL7197342	0.82	TAAR1 (0.51)	MAOBTAAR1SCN8AMAPTIDH1
Bromide SCHEMBL7200811	0.81	ACHE (0.55)	MAOBTAAR1ACHEHSD17B2CMA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5310853-A	Epoxy resins	THE DOW CHEMICAL COMPANY (US)	1994-05-10	—	—	US	disclosed