Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 9/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.38 |
| ▸ | TACR3 | P29371 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326911 | 0.89 | ROCK2 (0.44) | CYP26A1MEN1LMNACYP3A4MAPT | |
| SCHEMBL8959414 | 0.88 | MAPT (0.44) | CYP26A1MEN1LMNACYP3A4MAPT | |
| SCHEMBL7356190 | 0.81 | CDC25B (0.43) | MEN1LMNACYP3A4MAPTCYP2C9 | |
| SCHEMBL7332244 | 0.80 | ALDH1A1 (0.41) | MEN1LMNACYP3A4MAPTCYP2C9 | |
| SCHEMBL7329704 | 0.79 | MAPT (0.42) | LMNAMAPTROCK2 | |
| SCHEMBL7332776 | 0.77 | ALDH1A1 (0.44) | CYP26A1MEN1LMNAKMT2ATACR3 | |
| SCHEMBL7326648 | 0.77 | ALDH1A1 (0.47) | CYP26A1MEN1LMNAMAPTKMT2A | |
| SCHEMBL7325460 | 0.74 | PTPRC (0.38) | CYP26A1MEN1MAPTKMT2A | |
| SCHEMBL13802920 | 0.72 | CASR (0.45) | CYP26A1MAPT | |
| SCHEMBL7321127 | 0.70 | ALDH1A1 (0.36) | MEN1MAPTKMT2ASMN1; SMN2TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610334-A1 | NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPII b?III a? RECEPTOR. | GENENTECH INC (US) | 1994-08-17 | — | — | EP | disclosed |