Triaziquone

Triaziquone

SCHEMBL9319019

CCCCCCCN.O=C1C=C(N2CC2)C(=O)C(N2CC2)=C1N1CC1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 8/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
ALDH1A1 P00352 1/20 0.38
TSHR P16473 1/20 0.38
EPHX1 P07099 1/20 0.38
TP53 P04637 1/20 0.36
MAPT P10636 1/20 0.36
STAT3 P40763 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
DNMT1 P26358 1/20 0.34
ALOX5 P09917 6/20 0.31
MPEG1 Q2M385 4/20 0.31
NSD2 O96028 1/20 0.31
TTR P02766 1/20 0.31
XIAP P98170 1/20 0.31
GPR84 Q9NQS5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Octadecylamine SCHEMBL11308593 1.00 DNM1 (0.38) DNM1MEN1KMT2AALDH1A1TSHR
Triaziquone SCHEMBL11793180 0.98 TP53 (0.36) DNM1MEN1KMT2AALDH1A1TSHR
Triaziquone SCHEMBL6830995 0.92 DNMT1 (0.39) MEN1KMT2ATP53MAPTSTAT3
Tetrabuthylammonium SCHEMBL9397471 0.84 SLC22A1 (0.36) ALDH1A1TSHRTP53MAPTSTAT3
Palmitic Acid SCHEMBL2321669 0.82 PPARG (0.46) MEN1KMT2AALDH1A1TSHRGPR84
Triaziquone SCHEMBL10874089 0.80 DNMT1 (0.32) DNM1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL8966183 0.80 AKR1B1 (0.44) MEN1KMT2AALDH1A1TSHRGPR84
Triaziquone SCHEMBL7926114 0.80 DNMT1 (0.33) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL5800741 0.79 DNMT1 (0.41) MEN1KMT2ATSHRTP53MAPT
Triaziquone SCHEMBL11198981 0.79 TP53 (0.34) MEN1KMT2AALDH1A1TP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0418068-B1 Manufacture of thermoplastic elastomer compositions SUMITOMO CHEMICAL CO (JP) 1994-01-05 EP disclosed
EP-0418068-A2 Manufacture of thermoplastic elastomer compositions SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-03-20 EP disclosed