Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 2/20 | 0.33 |
| ▸ | TDP2 | O95551 | 2/20 | 0.33 |
| ▸ | NSD2 | O96028 | 2/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GALK1 | P51570 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triaziquone SCHEMBL600168 | 0.95 | DNMT1 (0.40) | DNMT1TP53MAPTSTAT3HTT | |
| Triaziquone SCHEMBL9319019 | 0.92 | DNM1 (0.38) | DNMT1TP53MAPTSTAT3HTT | |
| Octadecylamine SCHEMBL11308593 | 0.92 | DNM1 (0.38) | DNMT1TP53MAPTSTAT3HTT | |
| Triaziquone SCHEMBL610295 | 0.91 | DNMT1 (0.42) | DNMT1TP53MAPTSTAT3HTT | |
| Triaziquone SCHEMBL11793180 | 0.91 | TP53 (0.36) | DNMT1TP53MAPTSTAT3HTT | |
| Triaziquone SCHEMBL2160619 | 0.89 | DNMT1 (0.41) | DNMT1TP53MAPTSTAT3HTT | |
| Triaziquone SCHEMBL10379983 | 0.89 | DNMT1 (0.41) | DNMT1TP53MAPTSTAT3HTT | |
| Triaziquone SCHEMBL8171951 | 0.88 | CA12 (0.40) | DNMT1TP53MAPTSTAT3HTT | |
| Triaziquone SCHEMBL11416072 | 0.88 | DNMT1 (0.40) | DNMT1TP53MAPTSTAT3HTT | |
| Triaziquone SCHEMBL11644813 | 0.87 | DNMT1 (0.35) | DNMT1TP53MAPTSTAT3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6809159-B2 | VISCOSITY; MINIMAL IMPACT ON HEAT DEFLECTION TEMPERATURE, IMPACT PROPERTIES AND FLAME RETARDANCE | GENERAL ELECTRIC COMPANY | 2004-10-26 | — | — | US | disclosed |
| US-6794450-B2 | ENHANCING THE MELT FLOW, BLENDING WITH A POLYESTERS; RECEPTIVITY | GENERAL ELECTRIC COMPANY | 2004-09-21 | — | — | US | disclosed |
| US-20030171503-A1 | High flow compositions of compatibilized poly(arylene ether) polyamide blends | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2003-09-11 | — | — | US | disclosed |
| US-20020151652-A1 | High flow polyphenylene ether formulations with dendritic polymers | CITIBANK, N.A., AS COLLATERAL AGENT | 2002-10-17 | — | — | US | disclosed |