Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 3/20 | 0.34 |
| ▸ | APAF1 | O14727 | 2/20 | 0.34 |
| ▸ | TDP2 | O95551 | 2/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GALK1 | P51570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triaziquone SCHEMBL11791565 | 0.96 | DNMT1 (0.39) | DNMT1HTTTP53MAPTSTAT3 | |
| Triaziquone SCHEMBL1961248 | 0.93 | DNMT1 (0.39) | DNMT1HTTTP53MAPTSTAT3 | |
| Triaziquone SCHEMBL8585531 | 0.92 | HTT (0.37) | DNMT1HTTTP53MAPTSTAT3 | |
| Triaziquone SCHEMBL7616616 | 0.91 | DNMT1 (0.38) | DNMT1HTTTP53MAPTSTAT3 | |
| Triaziquone SCHEMBL3191414 | 0.91 | DNMT1 (0.38) | DNMT1HTTTP53MAPTSTAT3 | |
| Triaziquone SCHEMBL610295 | 0.91 | DNMT1 (0.42) | DNMT1HTTTP53MAPTSTAT3 | |
| Triaziquone SCHEMBL7996887 | 0.90 | DNMT1 (0.37) | DNMT1HTTTP53MAPTSTAT3 | |
| Triaziquone SCHEMBL3505984 | 0.90 | DNMT1 (0.37) | DNMT1HTTTP53MAPTSTAT3 | |
| Triaziquone SCHEMBL11350903 | 0.89 | HTT (0.42) | DNMT1HTTTP53MAPTSTAT3 | |
| Triaziquone SCHEMBL242425 | 0.89 | DNMT1 (0.41) | DNMT1HTTTP53MAPTSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006079364-A1 | SPECIFIC AND MILD PEPTIDE OR AMIDE BOND CLEAVAGE | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2006-08-03 | — | — | WO | disclosed |
| US-20030092767-A1 | Combination therapy for the treatment of inflammatory and respiratory diseases | ELI LILLY AND COMPANY | 2003-05-15 | — | — | US | disclosed |
| US-20020198138-A1 | Combination therapy for the treatment of inflammatory and respiratory diseases | ELI LILLY AND COMPANY | 2002-12-26 | — | — | US | disclosed |
| EP-0754948-B1 | Method for measuring the amount of constituent contained in specific lipotrotein | WAKO PURE CHEM IND LTD (JP) | 2001-10-17 | — | — | EP | disclosed |
| US-5962439-A | CARDIOVASCULAR DISORDER | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5849919-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor anonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0548949-B1 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-09-17 | — | — | EP | disclosed |
| US-5596009-A | TREATMENT OF THROMBOSIS, ATHERIOSCLEROSIS, ANTIISCHEMIC AGENTS, ANTIULCER AGENTS OR HYPOTENSIVE AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-01-21 | — | — | US | disclosed |
| US-5589496-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor agonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-12-31 | — | — | US | disclosed |
| EP-0578847-B1 | Fused benzeneoxyacetic acid derivatives and their use as PG12 antagonists | ONO PHARMACEUTICAL CO (JP) | 1996-10-09 | — | — | EP | disclosed |
| US-5336681-A | Elastase inhibitors | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-08-09 | — | — | US | disclosed |
| EP-0578847-A1 | Fused benzeneoxyacetic acid derivatives and their use as PG12 antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-01-19 | — | — | EP | disclosed |
| EP-0347168-B1 | DERIVATIVES OF P-SUBSTITUTED PHENYL ESTER OF PIVALIC ACID | ONO PHARMACEUTICAL CO (JP) | 1993-09-01 | — | — | EP | disclosed |
| EP-0548949-A2 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |
| US-5017610-A | Elastase inhibitor | ONO PHARMACEUTICAL CO., LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0347168-A1 | Derivatives of p-substituted phenyl ester of pivalic acid | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-12-20 | — | — | EP | disclosed |
| EP-0013617-B1 | PENICILLIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING CERTAIN OF THESE COMPOUNDS | BEECHAM GROUP PLC (GB) | 1984-07-04 | — | — | EP | disclosed |
| US-4347182-A | Preparation of penicillanic acid derivatives | BEECHAM GROUP LIMITED (GB) | 1982-08-31 | — | — | US | disclosed |
| EP-0013617-A1 | Penicillin derivatives, process for their preparation and pharmaceutical compositions containing certain of these compounds | BEECHAM GROUP PLC (GB) | 1980-07-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020198138-A1 | Combination therapy for the treatment of inflammatory and respiratory diseases | SERPINB1, ELANE, MPO | DNMT1 4779/4885HTT 2473/4885TP53 3425/4885 |
| US-20030092767-A1 | Combination therapy for the treatment of inflammatory and respiratory diseases | SERPINB1, ELANE, SPINT2 | DNMT1 4450/4885HTT 3892/4885TP53 4537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.