Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | GLA | P06280 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.59 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.59 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9319004 | 0.88 | MAPT (0.59) | MAPTKDM4EGLATDP1ALDH1A1 | |
| SCHEMBL11473415 | 0.84 | KDM4E (0.59) | MAPTKDM4EGLATDP1ALDH1A1 | |
| SCHEMBL554460 | 0.82 | KDM4E (0.64) | MAPTKDM4EGLATDP1ALDH1A1 | |
| SCHEMBL11544710 | 0.81 | MAPT (0.67) | MAPTKDM4EGLATDP1ALDH1A1 | |
| SCHEMBL9283208 | 0.80 | MAPT (0.69) | MAPTKDM4EGLATDP1ALDH1A1 | |
| SCHEMBL8981903 | 0.80 | ALDH1A1 (0.54) | MAPTKDM4EGLATDP1ALDH1A1 | |
| SCHEMBL3138995 | 0.79 | KDM4E (0.64) | MAPTKDM4EGLATDP1ALDH1A1 | |
| SCHEMBL9319047 | 0.79 | MAPT (0.70) | MAPTKDM4EGLATDP1ALDH1A1 | |
| Lactic Acid SCHEMBL3144656 | 0.78 | MAPT (0.55) | MAPTKDM4EGLATDP1ALDH1A1 | |
| SCHEMBL29276483 | 0.77 | ALDH1A1 (0.61) | MAPTKDM4EGLATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5308545-A | Pyrazoline compounds | CIBA-GEIGY CORPORATION (US) | 1994-05-03 | — | — | US | disclosed |
| US-4816590-A | Pyrazoline compounds and method of whitening | CIBA-GEIGY CORPORATION (US) | 1989-03-28 | — | — | US | disclosed |