Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.58 |
| ▸ | CA9 | Q16790 | 5/20 | 0.58 |
| ▸ | GAPDH | P04406 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 4/20 | 0.56 |
| ▸ | CA6 | P23280 | 4/20 | 0.56 |
| ▸ | CA7 | P43166 | 4/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.56 |
| ▸ | CA5A | P35218 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | CA4 | P22748 | 3/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | CA3 | P07451 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SLC16A3 | O15427 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | GPR35 | Q9HC97 | 11/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10650556 | 0.86 | CA12 (0.56) | CA12CA9GAPDHCA1CA6 | |
| SCHEMBL13740054 | 0.85 | CA12 (0.66) | CA12CA9CA1CA6CA7 | |
| SCHEMBL10961838 | 0.83 | CA12 (0.52) | CA12CA9CA1CA6CA7 | |
| SCHEMBL4101829 | 0.82 | SLC16A3 (0.74) | CA12CA9CA1CA6CA7 | |
| SCHEMBL11337643 | 0.82 | CA12 (0.74) | CA12CA9GAPDHCA1CA6 | |
| SCHEMBL27866083 | 0.80 | GPR35 (0.70) | CA12CA9CA1CA6CA7 | |
| SCHEMBL25697015 | 0.78 | CA12 (0.61) | CA12CA9CA1CA6CA7 | |
| SCHEMBL25696504 | 0.78 | CA12 (0.61) | CA12CA9CA1CA6CA7 | |
| SCHEMBL11512228 | 0.78 | CA12 (0.66) | CA12CA9CA1CA6CA7 | |
| SCHEMBL25209186 | 0.77 | GPR35 (0.60) | CA12CA9CA1CA6CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371220-A | Bicyclo-heterocyclic intermediates for cephalosporin compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-12-06 | — | — | US | disclosed |
| US-5232918-A | Bactericides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-08-03 | — | — | US | disclosed |
| US-5019570-A | Antibioics | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-05-28 | — | — | US | disclosed |
| US-4468394-A | Cephalosporin compounds | EISAI CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4415567-A | A 7B-CHROMONE-3-CARBOXAMIDO-2-/4-HYDROXY PHENYL/ACETAMIDO-2-CEPHEM DERIVATIVE | EISAI CO., LTD. (JP) | 1983-11-15 | — | — | US | disclosed |
| EP-0062328-A2 | Novel penicillin and cephalosporin compounds, a process for preparing the same and antibacterial composition containing the novel compounds | Eisai Co., Ltd. (JP) | 1982-10-13 | — | — | EP | disclosed |
| US-4344944-A | 7-α-methoxycephalosporin derivatives, and antibacterial drugs onctaining the same | EISAI CO., LTD. (JP) | 1982-08-17 | — | — | US | disclosed |
| EP-0054578-A1 | N-(substituted chromone-3-carbonyl)-phenylglycine derivatives | Eisai Co., Ltd. (JP) | 1982-06-30 | — | — | EP | disclosed |
| US-4331606-A | BACTERICIDES, CEPHALOSPORIN INTERMEDIATES | EISAI CO., LTD. (JP) | 1982-05-25 | — | — | US | disclosed |
| US-4285941-A | ANTIBIOTICS | EISAI CO., LTD. (JP) | 1981-08-25 | — | — | US | disclosed |
| US-4285940-A | ANTIBIOTICS | EISAI CO., LTD. (JP) | 1981-08-25 | — | — | US | disclosed |
| US-4285939-A | ANTIBIOTICS | EISAI CO., LTD. (JP) | 1981-08-25 | — | — | US | disclosed |