SCHEMBL11337643

SCHEMBL11337643

CC(=O)Oc1ccc2oc(=O)c(C(=O)O)cc2c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.74
CA9 Q16790 5/20 0.74
ALDH1A1 P00352 5/20 0.74
KDM4E B2RXH2 5/20 0.74
CA2 P00918 4/20 0.74
CA1 P00915 4/20 0.74
CA6 P23280 4/20 0.74
CA7 P43166 4/20 0.74
CA14 Q9ULX7 4/20 0.74
CA5B Q9Y2D0 4/20 0.74
CA5A P35218 3/20 0.74
CA3 P07451 3/20 0.74
HPGD P15428 2/20 0.74
GAPDH P04406 4/20 0.65
CA4 P22748 3/20 0.62
MAOB P27338 3/20 0.62
FLT3 P36888 1/20 0.61
MAOA P21397 1/20 0.60
GPR35 Q9HC97 3/20 0.58
GRIN1 Q05586 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4101829 0.89 SLC16A3 (0.74) CA12CA9ALDH1A1KDM4ECA2
SCHEMBL11356464 0.87 GAPDH (0.64) CA12CA9ALDH1A1KDM4ECA2
SCHEMBL978456 0.85 KDM4E (1.00) CA12CA9ALDH1A1KDM4ECA2
SCHEMBL29963204 0.85 KDM4E (1.00) CA12CA9ALDH1A1KDM4ECA2
SCHEMBL9319136 0.82 CA12 (0.58) CA12CA9ALDH1A1KDM4ECA2
SCHEMBL11337551 0.82 ALDH1A1 (0.72) CA12CA9ALDH1A1KDM4ECA2
SCHEMBL6416119 0.81 KDM4E (0.75) CA12CA9ALDH1A1KDM4ECA2
SCHEMBL17893712 0.80 ALDH1A1 (0.70) CA12CA9ALDH1A1KDM4ECA2
SCHEMBL26603107 0.80 KDM4E (0.69) CA12CA9ALDH1A1KDM4ECA2
SCHEMBL980363 0.79 ALDH1A1 (0.68) CA12CA9ALDH1A1KDM4ECA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4303664-A Novel penicillin derivatives containing a coumarin nucleus and medicines containing the same TEIJIN LIMITED (JP) 1981-12-01 US disclosed
US-4285941-A ANTIBIOTICS EISAI CO., LTD. (JP) 1981-08-25 US disclosed
US-4159268-A ANTIBIOTICS, MICROBIOCIDES AMERICAN CYANAMID COMPANY (US) 1979-06-26 US disclosed