Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 5/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.66 |
| ▸ | GLA | P06280 | 4/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | GAA | P10253 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | CASP1 | P29466 | 1/20 | 0.64 |
| ▸ | CASP7 | P55210 | 1/20 | 0.64 |
| ▸ | CA12 | O43570 | 4/20 | 0.62 |
| ▸ | CA9 | Q16790 | 4/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 4/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5940913 | 0.90 | GAA (0.76) | SLC16A3KDM4EGLARAB9ANPC1 | |
| SCHEMBL29378625 | 0.90 | KDM4E (0.65) | SLC16A3KDM4EGLARAB9ANPC1 | |
| SCHEMBL557449 | 0.90 | KDM4E (0.65) | SLC16A3KDM4EGLARAB9ANPC1 | |
| SCHEMBL11337643 | 0.89 | CA12 (0.74) | SLC16A3KDM4EALDH1A1GAAHPGD | |
| SCHEMBL2336577 | 0.87 | KDM4E (0.62) | SLC16A3KDM4EGLARAB9ANPC1 | |
| SCHEMBL6836395 | 0.87 | ALDH1A1 (0.79) | SLC16A3KDM4EGLARAB9ANPC1 | |
| SCHEMBL31222311 | 0.86 | SLC16A3 (0.74) | SLC16A3KDM4EGLARAB9ANPC1 | |
| SCHEMBL203997 | 0.85 | SLC16A3 (1.00) | SLC16A3KDM4EGLARAB9ANPC1 | |
| Glucuronate SCHEMBL7823446 | 0.84 | SLC16A3 (0.55) | SLC16A3KDM4EGLARAB9ANPC1 | |
| SCHEMBL5940918 | 0.84 | KDM4E (0.58) | SLC16A3KDM4EGLARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221442-A1 | SUBSTRATES AND SCREENING METHODS FOR TRANSPORT PROTEINS | XENOPORT, INC. (US) | 2009-09-03 | — | — | US | disclosed |
| US-7413536-B1 | Substrates and screening methods for transport proteins | XENOPORT, INC. (US) | 2008-08-19 | — | — | US | disclosed |
| EP-1212619-B1 | SUBSTRATES AND SCREENING METHODS FOR TRANSPORT PROTEINS | XENOPORT INC (US) | 2007-05-23 | — | — | EP | disclosed |
| EP-1212619-A4 | SUBSTRATES AND SCREENING METHODS FOR TRANSPORT PROTEINS | XENOPORT INC (US) | 2004-12-08 | — | — | EP | disclosed |
| US-20030224473-A1 | Methods for screening for histone deacetylase activity and for identifying histone deacetylase inhibitors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-12-04 | — | — | US | disclosed |
| WO-2001020331-A9 | SUBSTRATES AND SCREENING METHODS FOR TRANSPORT PROTEINS | XENOPORT INC (US) | 2002-10-03 | — | — | WO | disclosed |
| EP-1212619-A1 | SUBSTRATES AND SCREENING METHODS FOR TRANSPORT PROTEINS | Xenoport, Inc. (US) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001020331-A1 | SUBSTRATES AND SCREENING METHODS FOR TRANSPORT PROTEINS | XENOPORT, INC. (US) | 2001-03-22 | — | — | WO | disclosed |
| US-5512667-A | Trifunctional intermediates for preparing 3'-tailed oligonucleotides | DRUG ROYALTY LP1 (CA) | 1996-04-30 | — | — | US | disclosed |
| US-5419966-A | Solid support for synthesis of 3'-tailed oligonucleotides | MICROPROBE CORPORATION (US) | 1995-05-30 | — | — | US | disclosed |
| EP-0547142-A4 | — | MICROPROBE CORP (US) | 1995-01-18 | — | — | EP | disclosed |
| EP-0547142-A1 | SOLID SUPPORT SYNTHESIS OF 3'-TAILED OLIGONUCLEOTIDES VIA A LINKING MOLECULE | EPOCH PHARMACEUTICALS, INC. (US) | 1993-06-23 | — | — | EP | disclosed |
| WO-1992003464-A1 | SOLID SUPPORT SYNTHESIS OF 3'-TAILED OLIGONUCLEOTIDES VIA A LINKING MOLECULE | MICROPROBE CORPORATION (US) | 1992-03-05 | — | — | WO | disclosed |
| US-4303664-A | Novel penicillin derivatives containing a coumarin nucleus and medicines containing the same | TEIJIN LIMITED (JP) | 1981-12-01 | — | — | US | disclosed |
| US-4159268-A | ANTIBIOTICS, MICROBIOCIDES | AMERICAN CYANAMID COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030224473-A1 | Methods for screening for histone deacetylase activity and for identifying histone deacetylase inhibitors | HDAC1, HDAC5, HDAC11 | SLC16A3 3470/4885KDM4E 276/4885GLA 149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.