Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 5/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.41 |
| ▸ | PGK1 | P00558 | 3/20 | 0.40 |
| ▸ | GALR2 | O43603 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.33 |
| ▸ | IGFBP5 | P24593 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9319179 | 0.81 | PGK1 (0.58) | PGK1ALDH1A1 | |
| SCHEMBL9319282 | 0.80 | MAPT (0.56) | PIM1PIM2LMNAPOLBALDH1A1 | |
| SCHEMBL9318791 | 0.74 | PIM1 (0.50) | PIM1 | |
| SCHEMBL9319709 | 0.72 | ALDH1A1 (0.42) | PIM1PIM2LMNAPOLBALDH1A1 | |
| SCHEMBL9319003 | 0.72 | ALDH1A1 (0.42) | PIM1LMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9871154 | 0.71 | ALDH1A1 (0.47) | PIM1LMNAPOLBALDH1A1MAPT | |
| SCHEMBL8658426 | 0.69 | MAPT (0.39) | PIM1PIM2LMNAPOLBALDH1A1 | |
| SCHEMBL9453105 | 0.68 | KDM4C (0.32) | PIM1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9873241 | 0.67 | ALDH1A1 (0.41) | PIM1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2179646 | 0.66 | ALDH1A1 (0.48) | LMNAPOLBALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371220-A | Bicyclo-heterocyclic intermediates for cephalosporin compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-12-06 | — | — | US | disclosed |
| US-5019570-A | Antibioics | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-05-28 | — | — | US | disclosed |