Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PIM1 | P11309 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.39 |
| ▸ | CDK9 | P50750 | 3/20 | 0.39 |
| ▸ | CLK1 | P49759 | 2/20 | 0.39 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30583760 | 0.79 | ALDH1A1 (0.52) | ALDH1A1MAPTSMN1; SMN2PIM1CA12 | |
| SCHEMBL891835 | 0.79 | ALDH1A1 (0.52) | ALDH1A1MAPTSMN1; SMN2PIM1CA12 | |
| SCHEMBL29012657 | 0.76 | ALDH1A1 (0.48) | ALDH1A1MAPTSMN1; SMN2PIM1CA12 | |
| SCHEMBL3558607 | 0.76 | SMN1; SMN2 (0.57) | ALDH1A1MAPTSMN1; SMN2PIM1DYRK1A | |
| SCHEMBL9200853 | 0.75 | ACHE (0.46) | ALDH1A1MAPTCA1CA2ACHE | |
| SCHEMBL14917525 | 0.74 | DHODH (0.53) | ALDH1A1MAPTSMN1; SMN2CA12CA1 | |
| SCHEMBL2908140 | 0.71 | KDM4E (0.46) | ALDH1A1MAPTSMN1; SMN2CA12CA1 | |
| SCHEMBL8336160 | 0.71 | ALDH1A1 (0.47) | ALDH1A1MAPTSMN1; SMN2PIM1CA12 | |
| SCHEMBL9688082 | 0.68 | ACHE (0.59) | ALDH1A1MAPTSMN1; SMN2PIM1CA12 | |
| SCHEMBL7968125 | 0.68 | ACHE (0.59) | ALDH1A1MAPTSMN1; SMN2PIM1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371220-A | Bicyclo-heterocyclic intermediates for cephalosporin compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-12-06 | — | — | US | disclosed |