Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | GAA | P10253 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17866953 | 0.79 | ELANE (0.44) | ACHEMAPTGAAKMT2AALDH1A1 | |
| SCHEMBL29487399 | 0.79 | PDPK1 (0.39) | ACHEMAPTGAAKMT2AALDH1A1 | |
| SCHEMBL30808346 | 0.79 | ACHE (0.34) | ACHEMAPTGAAKMT2AALDH1A1 | |
| SCHEMBL9319451 | 0.75 | ALDH1A1 (0.47) | ACHEMAPTGAAKMT2AALDH1A1 | |
| SCHEMBL16011941 | 0.75 | ALDH1A1 (0.53) | ACHEMAPTKMT2AALDH1A1RAB9A | |
| SCHEMBL28749588 | 0.75 | ELANE (0.36) | KMT2AALDH1A1MEN1L3MBTL1 | |
| SCHEMBL482752 | 0.74 | ACHE (0.46) | ACHEMAPTGAAKMT2AALDH1A1 | |
| SCHEMBL26616704 | 0.72 | GPR35 (0.48) | MAPTKMT2AALDH1A1NPSR1MEN1 | |
| SCHEMBL27248935 | 0.71 | KCNH2 (0.38) | MAPTKMT2AALDH1A1RAB9AMEN1 | |
| SCHEMBL27248729 | 0.71 | TLR8 (0.40) | ACHEMAPTKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687249-A1 | BALANOIDS | ELI LILLY AND COMPANY (US) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020062-A2 | BALANOIDS AS PROTEIN KINASE C INHIBITORS | ELI LILLY AND COMPANY (US) | 1994-09-15 | — | — | WO | disclosed |