SCHEMBL9319967

SCHEMBL9319967

C=C(CN(CC)CC)C(=O)NC(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.35
TSHR P16473 1/20 0.34
MAPK1 P28482 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
FAAH O00519 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33
HTT P42858 1/20 0.33
OPRK1 P41145 1/20 0.32
MAPT P10636 3/20 0.32
LMNA P02545 2/20 0.32
CYP3A4 P08684 1/20 0.32
MC4R P32245 1/20 0.32
SCN4A P35499 1/20 0.32
MC3R P41968 1/20 0.32
HTR3A P46098 1/20 0.32
SCN5A Q14524 1/20 0.32
SCN9A Q15858 1/20 0.32
SCN3A Q9NY46 1/20 0.32
EPHX1 P07099 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9319960 0.82 EGFR (0.39) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL8643965 0.79 TSHR (0.39) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL7724917 0.77 ALDH1A1 (0.50) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL25762106 0.77 TSHR (0.38) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL28422625 0.75 MEN1 (0.44) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL20315008 0.75 CHRM2 (0.35) ALDH1A1MAPK1MAPTLMNACYP3A4
SCHEMBL15542907 0.74 MAPT (0.36) ALDH1A1MAPK1MAPTLMNACYP3A4
SCHEMBL25762110 0.74 TSHR (0.39) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL9320141 0.73 TSHR (0.40) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL522156 0.72 TSHR (0.38) ALDH1A1TSHRMAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0428970-B1 Process for preparing aqueous solutions or suspensions of quaternization products of tertiary aminoalkylesters or tertiary aminoalkylamides of acrylic or methacrylic acid, for instance of dimethylaminoethyl-acrylate-methochloride BASF AG (DE) 1994-01-19 EP disclosed
EP-0428970-A1 Process for preparing aqueous solutions or suspensions of quaternization products of tertiary aminoalkylesters or tertiary aminoalkylamides of acrylic or methacrylic acid, for instance of dimethylaminoethyl-acrylate-methochloride BASF Aktiengesellschaft (DE) 1991-05-29 EP disclosed
US-4647606-A Blend of rapid set asphaltic emulsion with slow set asphalt emulsion OWENS-CORNING FIBERGLAS CORPORATION (US) 1987-03-03 US disclosed
EP-0113038-B1 PROCESS FOR PREPARING CONCENTRATED AQUEOUS SOLUTIONS OF QUATERNIZED PRODUCTS FROM TERTIARY AMINO ALKYL ESTERS OR AMIDES OF ACRYLIC OR METHACRYLIC ACIDS BASF Aktiengesellschaft (DE) 1986-09-10 EP disclosed
US-4547225-A Additives for hot mix asphalt OWENS-CORNING FIBERGLAS CORPORATION (US) 1985-10-15 US disclosed
US-4520210-A ALKYLATION IN WATER SOLUBLE KETONE THEN SEPARATION BASF AKTIENGESELLSCHAFT (DE) 1985-05-28 US disclosed
EP-0082056-B1 CATIONIC ACRYLAMIDE AND RUBBER MODIFIED ASPHALTS OWENS-CORNING FIBERGLAS CORPORATION (US) 1985-05-22 EP disclosed
EP-0113038-A2 Process for preparing concentrated aqueous solutions of quaternized products from tertiary amino alkyl esters or amides of acrylic or methacrylic acids BASF Aktiengesellschaft (DE) 1984-07-11 EP disclosed
US-4456633-A Chip seal technique employing blends of asphaltic emulsions OWENS-CORNING FIBERGLAS CORPORATION (US) 1984-06-26 US disclosed
US-4436864-A Aqueous emulsions of acrylamide and rubber modified asphalts OWENS-CORNING FIBERGLAS CORPORATION (US) 1984-03-13 US disclosed
US-4436767-A Slurry seal method using acrylamide and rubber modified asphaltic emulsion OWENS-CORNING FIBERGLAS CORPORATION (US) 1984-03-13 US disclosed
US-4419489-A Easily emulsifiable acrylamide and rubber modified asphalts OWENS-CORNING FIBERGLAS CORPORATION (US) 1983-12-06 US disclosed
US-4394481-A Cationic arcylamide and rubber modified asphalts OWENS-CORNING FIBERGLAS CORPORATION (US) 1983-07-19 US disclosed
WO-1983002115-A1 CATIONIC ACRYLAMIDE AND RUBBER MODIFIED ASPHALTS OWENS CORNING FIBERGLASS CORP (US) 1983-06-23 WO disclosed
EP-0082056-A1 Cationic acrylamide and rubber modified asphalts OWENS-CORNING FIBERGLAS CORPORATION (US) 1983-06-22 EP disclosed
US-4383081-A Cationic acrylamide chemically modified asphalts OWENS-CORNING FIBERGLAS CORPORATION (US) 1983-05-10 US disclosed