SCHEMBL9320095

SCHEMBL9320095

CCOC(=O)c1ccc(-n2sccc2=O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 1.00
HTT P42858 5/20 0.56
HPGD P15428 2/20 0.56
ALDH1A1 P00352 2/20 0.56
HSP90AA1 P07900 1/20 0.56
CACNA1B Q00975 1/20 0.56
APBA1 Q02410 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
KAT2B Q92831 4/20 0.55
EP300 Q09472 3/20 0.55
MPI P34949 1/20 0.55
PHOSPHO1 Q8TCT1 1/20 0.55
KAT2A Q92830 1/20 0.55
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
ESR1 P03372 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1899386 0.83 IDO1 (0.71) IDO1HTTHPGDALDH1A1TDP1
SCHEMBL28924298 0.81 IDO1 (0.67) IDO1HPGDALDH1A1HSP90AA1TDP1
SCHEMBL2136307 0.76 IDO1 (0.60) IDO1HTTHPGDALDH1A1HSP90AA1
SCHEMBL87450 0.75 CA1 (0.83) HTTHPGDALDH1A1HSP90AA1CACNA1B
SCHEMBL9616912 0.74 IDO1 (0.59) IDO1HPGDALDH1A1KAT2BEP300
SCHEMBL9263510 0.74 SMN1; SMN2 (0.60) IDO1HTTHPGDALDH1A1HSP90AA1
SCHEMBL29504635 0.73 CA1 (0.79) HTTHPGDALDH1A1HSP90AA1CACNA1B
SCHEMBL30271267 0.73 CA1 (0.79) HTTHPGDALDH1A1HSP90AA1CACNA1B
SCHEMBL21440358 0.73 CA1 (0.79) HTTHPGDALDH1A1HSP90AA1CACNA1B
SCHEMBL7746905 0.73 CA1 (0.79) HTTHPGDALDH1A1HSP90AA1CACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3980400-B1 PEPTIDOMIMETICS FOR THE TREATMENT OF CORONAVIRUS AND PICORNAVIRUS INFECTIONS UNIV EMORY (US) 2025-08-06 EP disclosed
US-20250114389-A1 NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS UNIV EMORY (US) 2025-04-10 US disclosed
US-12268723-B2 Peptidomimetics for the treatment of coronavirus and picorna virus infections EMORY UNIVERSITY (US) 2025-04-08 US disclosed
US-20240238323-A1 MODIFIED NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS FOR CORONA AND OTHER VIRUSES EMORY UNIVERSITY 2024-07-18 US disclosed
US-20240216413-A1 THIONUCLEOSIDES AS ANTIVIRAL AGENTS EMORY UNIVERSITY (US) 2024-07-04 US disclosed
CN-117881403-A Thionucleosides as antiviral agents 爱莫里大学 2024-04-12 CN disclosed
CN-117858711-A Nucleoside and nucleotide analogs as antiviral agents 爱莫里大学 2024-04-09 CN disclosed
EP-4319764-A2 THIONUCLEOSIDES AS ANTIVIRAL AGENTS Emory University (US) 2024-02-14 EP disclosed
EP-4319763-A2 MODIFIED NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS FOR CORONA AND OTHER VIRUSES Emory University (US) 2024-02-14 EP disclosed
EP-4319762-A2 NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS Emory University (US) 2024-02-14 EP disclosed
US-11207370-B2 Peptidomimetics for the treatment of coronavirus and picornavirus infections EMORY UNIVERSITY (US) 2021-12-28 US disclosed
US-20210008150-A1 PEPTIDOMIMETICS FOR THE TREATMENT OF CORONAVIRUS AND PICORNAVIRUS INFECTIONS EMORY UNIVERSITY 2021-01-14 US disclosed
WO-2020247665-A1 PEPTIDOMIMETICS FOR THE TREATMENT OF CORONAVIRUS AND PICORNAVIRUS INFECTIONS EMORY UNIVERSITY (US) 2020-12-10 WO disclosed
EP-0331319-B1 Method for the formation of images KONISHIROKU PHOTO IND (JP) 1994-01-26 EP disclosed
US-H1090-H High contrast; hydrazide, isothizolone, bromonitroalcohol KONICA CORPORATION (JP) 1992-08-04 US disclosed
EP-0356801-A1 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1990-03-07 EP disclosed
EP-0331319-A1 Method for the formation of images KONICA CORPORATION (JP) 1989-09-06 EP disclosed
EP-0090584-B1 LIGHT-SENSITIVE SILVER HALIDE PHOTOGRAPHIC MATERIAL KONICA CORPORATION (JP) 1986-12-03 EP disclosed
US-4490462-A CONTAINING ISOTHIAZOLIN-3-ONE MICROBIOCIDE OR FUNGICIDE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-12-25 US disclosed
EP-0090584-A2 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1983-10-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240216413-A1 THIONUCLEOSIDES AS ANTIVIRAL AGENTS MTAP, NSUN3, METTL3 IDO1 727/4885HTT 1282/4885HPGD 4098/4885
US-20210008150-A1 PEPTIDOMIMETICS FOR THE TREATMENT OF CORONAVIRUS AND PICORNAVIRUS INFECTIONS ACE2, SARS1, VIP IDO1 967/4885HTT 1949/4885HPGD 3750/4885
US-12268723-B2 Peptidomimetics for the treatment of coronavirus and picorna virus infections ACE2, SARS1, HAVCR2 IDO1 996/4885HTT 1855/4885HPGD 3654/4885
US-20250114389-A1 NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS PNP, MTAP, NOP2 IDO1 825/4885HTT 2478/4885HPGD 3411/4885
US-20240238323-A1 MODIFIED NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS FOR CORONA AND OTHER VIRUSES MTAP, PNP, SARS1 IDO1 1048/4885HTT 2980/4885HPGD 3721/4885
US-11207370-B2 Peptidomimetics for the treatment of coronavirus and picornavirus infections ACE2, SARS1, VIP IDO1 967/4885HTT 1949/4885HPGD 3750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.