SCHEMBL9320128

SCHEMBL9320128

O=C(C1=Cc2ccccc21)C1=Cc2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.38
MAOB P27338 1/20 0.38
CDC25B P30305 2/20 0.36
CDC25A P30304 1/20 0.36
ALDH1A1 P00352 4/20 0.36
CA9 Q16790 3/20 0.34
CA12 O43570 2/20 0.34
LMNA P02545 3/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
KDM4E B2RXH2 3/20 0.33
MAPT P10636 3/20 0.33
THRB P10828 3/20 0.33
RECQL P46063 3/20 0.33
HPGD P15428 2/20 0.33
PTPN22 Q9Y2R2 2/20 0.33
APAF1 O14727 2/20 0.33
TDP2 O95551 2/20 0.33
BCHE P06276 2/20 0.33
POLB P06746 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9495495 0.83 ATM (0.52) ALDH1A1LMNAKMT2AKDM4EMAPT
SCHEMBL30895284 0.83 MAOA (0.50) MAOAMAOBALDH1A1CA9CA12
SCHEMBL503745 0.83 MAOA (0.50) MAOAMAOBALDH1A1CA9CA12
SCHEMBL6907491 0.81 MAOA (0.36) MAOAMAOBCDC25BCDC25AALDH1A1
Hydrochloric Acid SCHEMBL26614007 0.81 MAOA (0.48) MAOAMAOBALDH1A1CA9CA12
SCHEMBL9460233 0.81 CDC25A (0.38) MAOAMAOBCDC25BCDC25AALDH1A1
SCHEMBL10747127 0.80 KMT2A (0.45) ALDH1A1MEN1KMT2AHPGDPOLB
SCHEMBL6706620 0.79 LMNA (0.43) MAOAMAOBCDC25BCDC25AALDH1A1
Ethylene SCHEMBL28442445 0.79 MAOA (0.47) MAOAMAOBALDH1A1CA9CA12
SCHEMBL11745008 0.76 GAA (0.41) CDC25BCDC25AALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5349095-A Process for preparing hydroxyalkylbenzocyclobutenes THE DOW CHEMICAL COMPANY (US) 1994-09-20 US disclosed