SCHEMBL9320159

SCHEMBL9320159

C=C(C)C(=O)NC(C)(C)CCCN(C)C

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 1/20 0.34
ALDH1A1 P00352 1/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 2/20 0.31
KDM4A O75164 5/20 0.30
KDM4C Q9H3R0 5/20 0.30
KDM5A P29375 1/20 0.30
KDM7A Q6ZMT4 1/20 0.30
PHF8 Q9UPP1 1/20 0.30
KDM2A Q9Y2K7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5074775 0.89 ALDH1A1 (0.32) ALDH1A1
SCHEMBL12161161 0.80 ALDH1A1 (0.44) ALDH1A1
SCHEMBL150441 0.79 ALDH1A1 (0.43) ALDH1A1
SCHEMBL10833650 0.78 IMPDH2 (0.33)
SCHEMBL13260026 0.76 MEN1 (0.35) PAOXALDH1A1
SCHEMBL8210939 0.76 TGFBR1 (0.37) ALDH1A1
SCHEMBL6462038 0.76 ALDH1A1 (0.34) ALDH1A1
SCHEMBL3422991 0.76 ALDH1A1 (0.34) ALDH1A1LMNA
SCHEMBL6232119 0.76 ALDH1A1 (0.52) ALDH1A1LMNA
SCHEMBL19881206 0.75 TGFBR1 (0.34) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0430963-B1 HYDROLYSIS RESISTANT VINYL LACTAM AMINO ACRYLAMIDE POLYMERS ISP INVESTMENTS INC (US) 1994-01-12 EP claimed
EP-0430963-A4 HYDROLYSIS RESISTANT VINYL LACTAM AMINO ACRYLAMIDE POLYMERS 1991-11-21 EP claimed
EP-0430963-A1 HYDROLYSIS RESISTANT VINYL LACTAM AMINO ACRYLAMIDE POLYMERS. GAF CHEMICALS CORP (US) 1991-06-12 EP claimed
WO-1990001920-A1 HYDROLYSIS RESISTANT VINYL LACTAM AMINO ACRYLAMIDE POLYMERS GAF CHEMICALS CORPORATION (US) 1990-03-08 WO claimed
EP-0430963-B1 HYDROLYSIS RESISTANT VINYL LACTAM AMINO ACRYLAMIDE POLYMERS ISP INVESTMENTS INC (US) 1994-01-12 EP disclosed
EP-0430963-A4 HYDROLYSIS RESISTANT VINYL LACTAM AMINO ACRYLAMIDE POLYMERS 1991-11-21 EP disclosed
EP-0430963-A1 HYDROLYSIS RESISTANT VINYL LACTAM AMINO ACRYLAMIDE POLYMERS. GAF CHEMICALS CORP (US) 1991-06-12 EP disclosed
US-4923694-A HAIR CONDITIONERS; (3-METHACRYLAMIDOPROPYL) TRIMETHYL AMMONIUM CHLORIDE-VINYLPYRROLIDONE COPOLYMER GAF CHEMICALS CORPORATION (US) 1990-05-08 US disclosed
WO-1990001920-A1 HYDROLYSIS RESISTANT VINYL LACTAM AMINO ACRYLAMIDE POLYMERS GAF CHEMICALS CORPORATION (US) 1990-03-08 WO disclosed