Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4235680 | 0.98 | TP53 (0.48) | TP53TAAR1SLC6A2CALM1TSHR | |
| Hydrochloric Acid SCHEMBL965647 | 0.95 | TP53 (0.46) | TP53TAAR1SLC6A2CALM1TSHR | |
| Bromide SCHEMBL1046180 | 0.87 | TP53 (0.46) | TP53TAAR1SLC6A2CALM1TSHR | |
| SCHEMBL2603135 | 0.85 | TP53 (0.48) | TP53TAAR1SLC6A2CALM1TSHR | |
| SCHEMBL395841 | 0.79 | TP53 (0.44) | TP53TAAR1SLC6A2CALM1TSHR | |
| Bromide SCHEMBL29399740 | 0.78 | TP53 (0.48) | TP53TAAR1SLC6A2CALM1TSHR | |
| Hydrochloric Acid SCHEMBL394410 | 0.77 | TP53 (0.42) | TP53TAAR1SLC6A2CALM1TSHR | |
| Bromide SCHEMBL7106052 | 0.77 | TP53 (0.46) | TP53TAAR1SLC6A2CALM1TSHR | |
| SCHEMBL390922 | 0.76 | TP53 (0.40) | TP53TAAR1SLC6A2CALM1TSHR | |
| Perchlorate SCHEMBL5034610 | 0.76 | TSHR (0.40) | TP53TAAR1SLC6A2CALM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0190054-B2 | Heat-processable color photosensitive material | KONISHIROKU PHOTO IND (JP) | 1994-01-12 | — | — | EP | disclosed |
| US-5071740-A | HEAT DEVELOPABLE COLOR PHOTOSENSITIVE MATERIAL | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1991-12-10 | — | — | US | disclosed |
| EP-0173584-B1 | HEAT-DEVELOPABLE COLOR PHOTO-SENSITIVE MATERIAL | KONICA CORPORATION (JP) | 1990-03-07 | — | — | EP | disclosed |
| EP-0174177-B1 | HEAT-DEVELOPABLE COLOR PHOTO-SENSITIVE MATERIAL | KONICA CORPORATION (JP) | 1989-11-29 | — | — | EP | disclosed |
| EP-0190054-B1 | HEAT-PROCESSABLE COLOR PHOTOSENSITIVE MATERIAL | KONICA CORPORATION (JP) | 1989-04-19 | — | — | EP | disclosed |
| US-4656124-A | CYAN-FORMING POLYMERIC CHROMOGEN FOR DIFFUSION TRANSFER; SHARPNESS | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1987-04-07 | — | — | US | disclosed |
| US-4650748-A | POLYMERIC DYES | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1987-03-17 | — | — | US | disclosed |
| US-4631251-A | Heat-developable color photo-sensitive material with polymeric coupler | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1986-12-23 | — | — | US | disclosed |
| EP-0190054-A2 | Heat-processable color photosensitive material | KONICA CORPORATION (JP) | 1986-08-06 | — | — | EP | disclosed |
| EP-0186494-A2 | Heat-developable color photo-sensitive material | KONICA CORPORATION (JP) | 1986-07-02 | — | — | EP | disclosed |
| EP-0174177-A2 | Heat-developable color photo-sensitive material | KONICA CORPORATION (JP) | 1986-03-12 | — | — | EP | disclosed |
| EP-0173584-A2 | Heat-developable color photo-sensitive material | KONICA CORPORATION (JP) | 1986-03-05 | — | — | EP | disclosed |
| EP-0157639-A2 | Heat-developable multilayered color photo-sensitive material | KONICA CORPORATION (JP) | 1985-10-09 | — | — | EP | disclosed |