Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 9/20 | 0.62 |
| ▸ | BRD4 | O60885 | 3/20 | 0.50 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | BRD1 | O95696 | 2/20 | 0.43 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL763370 | 0.84 | BRPF1 (0.59) | BRPF1BRD4BRD9CA12CA9 | |
| SCHEMBL9411117 | 0.83 | BRPF1 (0.57) | BRPF1BRD4BRD9CA12CA9 | |
| SCHEMBL4408021 | 0.83 | BRPF1 (0.57) | BRPF1BRD4BRD9CA12CA9 | |
| SCHEMBL13886419 | 0.81 | BRPF1 (0.56) | BRPF1BRD4BRD9CA12CA9 | |
| SCHEMBL17979482 | 0.81 | BRPF1 (0.41) | BRPF1CA12CA9ALOX5CA1 | |
| SCHEMBL14518794 | 0.80 | BRPF1 (0.54) | BRPF1BRD4BRD9CA12CA9 | |
| SCHEMBL13886461 | 0.78 | BRPF1 (0.51) | BRPF1BRD4BRD9CA12CA9 | |
| SCHEMBL7085783 | 0.77 | BRPF1 (1.00) | BRPF1BRD4BRD9CA12CA9 | |
| SCHEMBL12804294 | 0.75 | MEN1 (0.55) | CYP2D6 | |
| SCHEMBL21074449 | 0.74 | ASIC3 (0.42) | BRPF1CA12CA9CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350765-A | Treatment of allergic and inflammatory diseases | ABBOTT LABORATORIES (US) | 1994-09-27 | — | — | US | disclosed |
| WO-1994004528-A1 | ETHER-CONTAINING INHIBITORS OF 5-LIPOXYGENASE | ABBOTT LABORATORIES (US) | 1994-03-03 | — | — | WO | disclosed |
| US-5268379-A | Quinolin-1-one structure | ABBOTT LABORATORIES (US) | 1993-12-07 | — | — | US | disclosed |