Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 7/20 | 0.38 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9320525 | 0.95 | GRIN1 (0.44) | GRIN1GRIN2ASIGMAR1ALDH1A1KCNH2 | |
| SCHEMBL9320495 | 0.89 | HTR1A (0.44) | GRIN1GRIN2AKCNH2HTR1AADRA1D | |
| SCHEMBL9321203 | 0.87 | GRIN1 (0.44) | GRIN1GRIN2ASIGMAR1ALDH1A1KCNH2 | |
| SCHEMBL9322452 | 0.82 | HTR1A (0.41) | GRIN1GRIN2ASIGMAR1KCNH2HTR1A | |
| SCHEMBL9321171 | 0.80 | POLB (0.41) | HTR1AADRA1DADRA1AADRA1B | |
| Diphenylmethane SCHEMBL9321214 | 0.78 | MEN1 (0.46) | SIGMAR1ALDH1A1 | |
| SCHEMBL9319883 | 0.75 | HTR1A (0.48) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL7731055 | 0.74 | CYP19A1 (0.50) | SIGMAR1ALDH1A1 | |
| SCHEMBL6712611 | 0.74 | TDP1 (0.46) | ALDH1A1 | |
| SCHEMBL28923106 | 0.73 | ALDH1A1 (0.59) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0336391-B1 | Reversibly color-changeable materials | TEIJIN LTD (JP) | 1994-01-26 | — | — | EP | disclosed |
| US-5068062-A | Crosslinked resin containing 4,4*-diaminodiphenylmethane units with the amine quaternized and an electrolytic material | TEIJIN LIMITED (JP) | 1991-11-26 | — | — | US | disclosed |
| EP-0336391-A2 | Reversibly color-changeable materials | TEIJIN LIMITED (JP) | 1989-10-11 | — | — | EP | disclosed |