Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 4/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9320293 | 0.95 | GRIN1 (0.46) | GRIN1GRIN2AKCNH2SIGMAR1HTR1A | |
| SCHEMBL9320495 | 0.91 | HTR1A (0.44) | GRIN1GRIN2AKCNH2HTR1AADRA1D | |
| SCHEMBL9322452 | 0.86 | HTR1A (0.41) | GRIN1GRIN2AKCNH2SIGMAR1HTR1A | |
| SCHEMBL9321203 | 0.82 | GRIN1 (0.44) | GRIN1GRIN2AKCNH2SIGMAR1HTR1A | |
| SCHEMBL9321171 | 0.81 | POLB (0.41) | HTR1AADRA1DADRA1AADRA1BCHRM2 | |
| Diphenylmethane SCHEMBL9322223 | 0.78 | MEN1 (0.47) | SIGMAR1MEN1KMT2ACHRM2 | |
| SCHEMBL9319883 | 0.76 | HTR1A (0.48) | HTR1AADRA1DADRA1AADRA1BKMT2A | |
| SCHEMBL6712611 | 0.76 | TDP1 (0.46) | KMT2AALDH1A1CHRM2CHRM4CHRM5 | |
| SCHEMBL27994199 | 0.74 | TDP1 (0.49) | MEN1KMT2AALDH1A1CHRM2CHRM4 | |
| Diphenylmethane SCHEMBL9321214 | 0.73 | MEN1 (0.46) | SIGMAR1MEN1KMT2AALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0336391-B1 | Reversibly color-changeable materials | TEIJIN LTD (JP) | 1994-01-26 | — | — | EP | disclosed |
| EP-0336391-A2 | Reversibly color-changeable materials | TEIJIN LIMITED (JP) | 1989-10-11 | — | — | EP | disclosed |