Diphenylmethane

Diphenylmethane

SCHEMBL9322223

C(CNCCCC1CO1)CC1CO1.c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
SIGMAR1 Q99720 5/20 0.46
MGLL Q99685 2/20 0.43
CHRM2 P08172 1/20 0.43
CALM1 P0DP23 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylmethane SCHEMBL9321214 0.95 MEN1 (0.46) MEN1KMT2ASIGMAR1MGLLCHRM2
Diphenylmethane SCHEMBL9322376 0.89 MEN1 (0.46) MEN1KMT2AMGLLCHRM2CALM1
SCHEMBL9322452 0.79 HTR1A (0.41) MEN1KMT2ASIGMAR1CHRM2
Diphenylmethane SCHEMBL9322142 0.78 CALM1 (0.48) MGLLCHRM2CALM1
SCHEMBL9320525 0.78 GRIN1 (0.44) MEN1KMT2ASIGMAR1CHRM2
SCHEMBL9320157 0.76 ALDH1A1 (0.35) MEN1KMT2AMGLLCHRM2
SCHEMBL51024 0.76 MEN1 (0.69) MEN1KMT2AMGLL
SCHEMBL20695779 0.75 MEN1 (0.57) MEN1KMT2ACHRM2
SCHEMBL22204395 0.75 ALDH1A1 (0.57) MEN1KMT2ASIGMAR1
SCHEMBL16429266 0.75 MEN1 (0.57) MEN1KMT2ACHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0336391-B1 Reversibly color-changeable materials TEIJIN LTD (JP) 1994-01-26 EP disclosed
US-5068062-A Crosslinked resin containing 4,4*-diaminodiphenylmethane units with the amine quaternized and an electrolytic material TEIJIN LIMITED (JP) 1991-11-26 US disclosed
EP-0336391-A2 Reversibly color-changeable materials TEIJIN LIMITED (JP) 1989-10-11 EP disclosed