Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8295923 | 0.92 | RAB9A (0.33) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27378443 | 0.92 | RAB9A (0.33) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8296439 | 0.85 | GRM5 (0.36) | KDM1AMAOB | |
| SCHEMBL8301053 | 0.85 | L3MBTL1 (0.36) | HTTKDM1AMAOBGAANPSR1 | |
| SCHEMBL8301694 | 0.84 | PTGS1 (0.36) | HTTMETAP2NOTUMKDM1AMAOB | |
| SCHEMBL8302156 | 0.82 | GRM5 (0.35) | KDM1AALDH1A1HPGDKDM4E | |
| SCHEMBL9392792 | 0.79 | HTT (0.49) | HTTKDM1AMAOBALDH1A1HPGD | |
| SCHEMBL8296279 | 0.79 | GRM5 (0.32) | SMN1; SMN2 | |
| SCHEMBL8302450 | 0.77 | HTR3E (0.36) | HTTGAANPSR1NPC1RAB9A | |
| SCHEMBL8301703 | 0.76 | BACE1 (0.38) | HTTALDH1A1HPGDGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5324837-A | 3,4-disubstituted-4,5-dihydro-1H-pyrazoles and a method of preparation | DOWELANCO (US) | 1994-06-28 | — | — | US | disclosed |