Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | GRM5 | P41594 | 1/20 | 0.65 |
| ▸ | HTR1A | P08908 | 5/20 | 0.65 |
| ▸ | HTR7 | P34969 | 4/20 | 0.65 |
| ▸ | GFER | P55789 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | HTR6 | P50406 | 1/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321229 | 0.88 | KMT2A (0.74) | MEN1KMT2AALDH1A1GRM5TSHR | |
| SCHEMBL10911138 | 0.85 | POLB (0.68) | MEN1KMT2AALDH1A1SMN1; SMN2ATM | |
| SCHEMBL9321396 | 0.84 | KMT2A (0.62) | MEN1KMT2AKDM4EHTR1AHTR7 | |
| SCHEMBL264542 | 0.84 | MEN1 (0.74) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL4776950 | 0.82 | ALDH1A1 (0.73) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8091444 | 0.82 | MEN1 (0.80) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL16501806 | 0.81 | MEN1 (0.78) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL4352910 | 0.81 | MEN1 (0.79) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL10976943 | 0.81 | ATM (0.65) | MEN1KMT2AHTR1AHTR7ATM | |
| SCHEMBL10981282 | 0.81 | ATM (0.65) | MEN1KMT2AHTR1AHTR7ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310268-B1 | Substituted cycloalkanols | AMERICAN HOME PROD (US) | 1994-02-02 | — | — | EP | disclosed |
| US-4826844-A | ANTIDEPRESSANT, ANXIOLYTIC AGENT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-05-02 | — | — | US | disclosed |
| EP-0310268-A2 | Substituted cycloalkanols | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-04-05 | — | — | EP | disclosed |