Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.77 |
| ▸ | HTR1A | P08908 | 6/20 | 0.75 |
| ▸ | HTR7 | P34969 | 5/20 | 0.75 |
| ▸ | TSHR | P16473 | 2/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.73 |
| ▸ | HTR2A | P28223 | 1/20 | 0.64 |
| ▸ | HTR6 | P50406 | 1/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA9 | Q16790 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264542 | 0.88 | MEN1 (0.74) | MEN1KMT2AALDH1A1SMN1; SMN2HTR1A | |
| SCHEMBL9988385 | 0.84 | MAPT (0.76) | MEN1KMT2AALDH1A1SMN1; SMN2HTR1A | |
| SCHEMBL4776950 | 0.84 | ALDH1A1 (0.73) | MEN1KMT2AALDH1A1SMN1; SMN2HTR1A | |
| SCHEMBL3995728 | 0.83 | MEN1 (0.76) | MEN1KMT2AALDH1A1SMN1; SMN2HTR1A | |
| SCHEMBL17884620 | 0.83 | MEN1 (0.76) | MEN1KMT2AALDH1A1SMN1; SMN2HTR1A | |
| SCHEMBL8091444 | 0.83 | MEN1 (0.80) | MEN1KMT2AALDH1A1SMN1; SMN2HTR1A | |
| SCHEMBL9987526 | 0.83 | KMT2A (0.68) | MEN1KMT2AALDH1A1SMN1; SMN2HTR1A | |
| SCHEMBL17884795 | 0.82 | MEN1 (0.74) | MEN1KMT2AALDH1A1SMN1; SMN2HTR1A | |
| SCHEMBL30609637 | 0.82 | MEN1 (0.74) | MEN1KMT2AALDH1A1SMN1; SMN2HTR1A | |
| SCHEMBL17884942 | 0.82 | MEN1 (0.74) | MEN1KMT2AALDH1A1SMN1; SMN2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009105604-A1 | SUBSTITUTED TRIAZOLOPYRIDINES | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-08-27 | — | — | WO | disclosed |
| US-20090209550-A1 | SUBSTITUTED TRIAZOLOPYRIDINES | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-08-20 | — | — | US | disclosed |
| US-20090209550-A1 | SUBSTITUTED TRIAZOLOPYRIDINES | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-08-20 | — | — | US | disclosed |
| US-20090209550-A1 | SUBSTITUTED TRIAZOLOPYRIDINES | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209550-A1 | SUBSTITUTED TRIAZOLOPYRIDINES | HTR5A, HTR3A, HTR2C | MEN1 3990/4885KMT2A 4022/4885ALDH1A1 910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.