Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 2/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9323550 | 0.91 | TP53 (0.39) | KCNA3SPHK1SMN1; SMN2GBA1TP53 | |
| SCHEMBL9322261 | 0.83 | HRH3 (0.36) | SMN1; SMN2GBA1TP53 | |
| SCHEMBL13659629 | 0.81 | CARM1 (0.41) | KCNA3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL9323712 | 0.81 | SMN1; SMN2 (0.50) | CARM1PRMT6MEN1ALDH1A1KMT2A | |
| SCHEMBL9321389 | 0.80 | CARM1 (0.45) | CARM1PRMT6PRMT8ALDH1A1 | |
| SCHEMBL6957321 | 0.79 | KCNA3 (0.53) | KCNA3SPHK1GBA1 | |
| SCHEMBL11932479 | 0.75 | GBA1 (0.49) | KCNA3SPHK1GBA1 | |
| SCHEMBL9323677 | 0.75 | SMN1; SMN2 (0.39) | MEN1KMT2ASMN1; SMN2HSD17B10TP53 | |
| SCHEMBL22355887 | 0.75 | PDCD1 (0.38) | KCNA3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL18233594 | 0.75 | PDCD1 (0.38) | KCNA3CARM1PRMT6PRMT1PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310902-A | Glutamate blockers | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| US-5070196-A | GLUTAMATE BLOCKERS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |